Rehydration solution, oral

WHO-ORS, World Health Organization Oral Rehydration Solution. 

These diseases are generally self-limiting and are easily managed with oral rehydration solutions. 

Q74 Patients using oral rehydration salts should be advised that after reconstitution, any unused solution should be discarded no later than 1 hour after preparation unless stored in a refrigerator. Oral rehydration solutions should be slightly hypo-osmolar. 

Oral rehydration salts should be reconstituted with water. Patients are advised to put the reconstituted solution in the fridge or else it should be used up to 1 hour after reconstitution. Oral rehydration solution should be slightly hypo-osmolar to decrease the electrolyte and water loss from the intestines. 

Oral rehydration solution (g/L of boiled water NaQ 3.5, glucose 20, NaHCOs 2.5, KQ 1.5). Oral administration of glucose-containing salt solutions enables fluids to be absorbed because toxins do not impair the cotransport of Na+ and glucose (as well as of H2O) through the mucosal epithelium. In this manner, although frequent discharge of stool is not prevented, dehydration is successfully corrected. 

Hahn S, Kim Y, Garner P. Reduced osmolarity oral rehydration solution for treating dehydration caused by acute diarrhoea in children. Cochrane Database Syst Rev 2002. 

Tabacow, and N. L. Machado. Negative findings for use of coconut water as an oral rehydration solution in childhood diarrhea. J Am Coll Nutr 1993 12(2) 190-193. 

Lebenthal, E., U. Khin-Maung, D. D. K. Rolston, et al. Composition and preliminary evaluation of a hydrolyzed rice-based oral rehydration solution for the treatment of acute diarrhea in children. J Amer Coll Nutr 1995 14(3) 299-303. 

Mustafa, S. A., Z. E. A. Karrar, and J. I. A. Suliman. Cereal-based oral rehydration solutions in Sudanese children with diarrhoea A comparative clinical trial of rice-based and sorghum-based oral rehydration solutions. Ann Trop Paediat 1995 15(4) 313-319. 

Wapnir, R.A. and Lifshitz, F. (1985) Osmolality and solute concentration - their relationship with oral rehydration solution effectiveness an experimental assessment. Pediatric Research, 19 894-98. 

Jumarie Cand Malo C (1991) CACO-2 cells cultured in serum-free medium as a model for the study of enterocytic differentiation in vitro. J Cell Physiol 149 24-33 Karlsson J, Ungell AL, Artursson P (1994) Effect of an oral rehydration solution on paracellular drug transport in intestinal epithelial cells and tissues assessment of charge and tissue selectivity. Pharm Res 11 248... 

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