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Optical label-free biosensor

Dotsenko AV, Diikov AL, Vartanyan TA (2003) Label-free biosensor using an optical waveguide with induced Bragg grating of variable strength. Sens Actuators B 94 116-121... [Pg.173]

Rea I, Orabona E, Lamberti A, Rendina I, De Stefano L (2011) A microfluidics assisted porous silicon array for optical label-free biochemical sensing. Biomicrofluidics 5 034120 Rendina I, Rea I, Rotiroti L, De Stefano L (2007) Porous silicon based optical biosensors and biochips. Physica E 38(1-2) 188-192... [Pg.542]

Fig. 16.1 Convergence of optical and chemical localization to improve biosensor performance. For label free optical detection, ideally one would like to develop a system that maximizes the overlap between the optical localization (where the electromagnetic energy is concentrated) and the chemical localization (where the biomolecular target will be immobilized)... Fig. 16.1 Convergence of optical and chemical localization to improve biosensor performance. For label free optical detection, ideally one would like to develop a system that maximizes the overlap between the optical localization (where the electromagnetic energy is concentrated) and the chemical localization (where the biomolecular target will be immobilized)...
Surface plasmon resonance (SPR) technique had become popular in interaction studies between biological molecules (1). It is an optical biosensor, and the interactions can be detected by SPR angle shift or reflection light intensity. In typical SPR measurement, one of pair interacting biomolecules was immobilized on a gold chip, and another was flowed over the chip as its solution. There are two major advantages in SPR assay (a) real time evaluations on kinetics studies and (b) label-free measurements. [Pg.227]

A new type of label-free optical biosensor and the BIND system, similar to SPR, are described in detail by Cunningham and Laing (2008). These optical biosensors... [Pg.103]

Fang Y, Ferrie AM, Fontaine NH, Yuen PK (2005) Characteristics of dynamic mass redistribution of epidermal growth factor receptor signaling in living cells measured with label-free optical biosensors. Anal Chem 77 5720-5725... [Pg.52]

Optical biosensors including SPR and RWG are the most popular label-free techniques for detecting biomolecular interactions [12]. [Pg.34]

Fang Y (2006) Label-free cell-based assays with optical biosensors in drug discovery. Assay Drug Dev Technol 4 583-595... [Pg.40]

Fang Y, Ferric AM (2008) Label-free optical biosensor for ligand-directed functional selectivity acting on P2 adrenoceptor in bving cells. FEBS Lett 582 558-564... [Pg.40]

Biophotonics Optical biosensor Optical chemical sensor Label free Refractive index Sensing principles Protein DNA Vims Bacterium... [Pg.260]

Cunningham B, Lin B, Qiu J, Li P, Pepper J, Hugh B (2002) A plastic resonant optical biosensor for multiparallel detection of label-free biochemical interactions. Sens Actuators B 85 219-226... [Pg.141]

Direct detection biosensors utilize direct measurement of the biological interaction. Such detectors typically measure physical changes (e.g., changes in optical, mechanical, or electrical properties) induced by the biological interaction, and they do not require labeling (i.e., label free) for detection. Direct biosensors can also be used in an indirect mode, typically to increase their sensitivity. Direct detection systems include optical-based systems (most common being surface plasmon resonance) and mechanical systems such as quartz crystal resonators. [Pg.470]

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See also in sourсe #XX -- [ Pg.25 , Pg.26 , Pg.27 ]



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