Opioid analgesic activity

Levorphanol (Levo-Dromoran) is an L-isomer morphi-nan derivative of morphine that is five to seven times more potent than morphine. It produces all of the side effects associated with morphine but less nausea. It is indicated for moderate to severe pain as a preoperative anxiolytic. It is often used in combination with thiopental to reduce the latter drug s anesthetic dose and to decrease postoperative recovery time. The o-isomer of levorphanol, dextrorphan, does not possess opioid analgesic activity but is a useful antitussive. 

Yaksh, T.L. Pharmacology and mechanisms of opioid analgesic activity, Acta Anaesthesiol. Scand. 1997,... 

Bannon, A. W., Decker, M. W., Holladay, M. W., Curzon, P., Donnelly-Roberts, D. L., Puttfarcken, P. S., Bitner, R. S., Diaz, A., Dickenson, A. H., Porsolt, R. D., Williams, M., Arneric, S. P. Broad-spectrum, non-opioid analgesic activity by selective modulation of neuronal nicotinic acetylcholine receptors, Science 1998, 279, 77-81. 

BW 373U86 is a piperazir lbenzamide derivative, a (5) OPIOID RECEPTOR AGONIST with OPIOID ANALGESIC activity. 

P-casomorphin is a heptapeptide from bovine milk, a fragment from p-casein. It is an opioid receptor agonist and has OPIOID ANALGESIC activity. A tetrapeptide within this sequence, morphiceptin, also has opioid activity, catabolin interleukin-l. 

NIH 7343) is one of the phenylpiperidine series, an OPIOID RECEPTOR AGONIST, with OPIOID ANALGESIC activity, dipivefrine [ban, inn] (diplvefrin hydrochloride [usan] Propine and many other names) is a sympathomimetic that chemically is a prodrug which is converted within the eye into adrenaline. It can be used therapeutically in topical... 

NIH 5145) is a dithienyl compound, an opioid receptor AGONIST, with OPIOID ANALGESIC activity, ethylmorphine [ban] is the 3-ethyl ether of morphine, and is an OPIOID RECEPTOR AGONIST, with OPIOID ANALGESIC and ANTITUSSIVE activity. 

Levoprome methotrimeprazine. levopropicillin propicillin, levopropylcillin potassium propicillin, levopropoxyphene [ban, inn) (levopropoxyphene napsylate [usan) Lilly 29866) is one of the methadone series, the (2/f,35)-(-)-form of propoxyphene. It is an OPIOID RECEPTOR AGONIST, but has very slight OPIOID ANALGESIC activity. It can be used in ANTITUSSIVE preparations, levopropoxyphene napsylate ... 

LY 127623 BCW59-A) is a synthetic pentapeptide analogue of enkephalin, and is an opioid RECEPTOR agonist with OPIOID analgesic activity. 

OPIOID RECEPTOR AGONIST with OPIOID ANALGESIC activity. 

Pentasa mesalazine. pentazocine [ban,inn.jan,usan] (pentazocine hydrochloride [usan] pentazocine lactate [usan] NSC 107430 Fortagesic Fortral Talwin ) is one of the benzomorphan series and is a (mixed partial p and full k) OPIOID RECEPTOR AGONIST with OPIOID ANALGESIC activity. It is used orally or by injection to treat moderate to severe pain, pentazocine hydrochloride pentazocine, pentazocine lactate pentazocine, pentetrazol [ban, inn] (pentylenetetrazole pentamethylenetetrazole) has similar properties to doxapram as a CNS stimulant and respiratory stimulant. It was previously used intramuscularly to treat barbiturate and other CNS depressants in overdose, and orally for bronchial disorders. 

Gl 87084B Ultiva ) is one of the phenylpiperidine series, a (p) OPIOID RECEPTOR AGONIST with OPIOID ANALGESIC activity. It is an ultra-short acting analgesic, used intravenously during general anaesthesia. 

Syncurine decamethonium iodide, syndyphalin (Syndyphalin 33) is a synthetic pseudopeptide enkephalin analogue, and is an OPIOID RECEPTOR AGONIST with OPIOID ANALGESIC activity, syndyphalin 25 (SD 25) is a synthetic pseudopeptide enkephalin analogue, and is a (p) opioid RECEPTOR AGONIST with OPIOID ANALGESIC activity. 

THC 250 a-amylase. thebacon [ban, inn] (acetyldlhydrocodeinone demethyidihydrothebaine acetate) is one of the phenanthrene series, and is an OPIOID RECEPTOR AGONIST active as an opioid analgesic and antitussive. thebaine (codeinone methyl enol ether paramorphine) is one of the phenanthrene series of alkaloid from Papaver spp in particular Papaver bracteatum (Papaveraceae). It has OPIOID RECEPTOR AGONIST and OPIOID ANALGESIC activity, but... 

Win 42156-2) is a benzazocin derivative, a mixed OPIOID RECEPTOR AGONIST and OPIOID RECEPTOR ANTAGONIST with OPIOID ANALGESIC activity, tonazocine mesylate tonazocine. 

Tramake Tramal Zydol ) is a phenylcyclohexanol derivative, a (p) OPIOID RECEPTOR agonist with partial OPIOID ANALGESIC activity. It is also a monoamine (serotonin and noradrenaline) re-UPTAKE inhibitor, and this mechanism is thought independently to contribute a component to analgesic activity. 

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