Ontogenetic patterns

With some of the phase 2 metabolizing enzymes, there may be strict ontogenetic patterns of expression. Sulfate conjugation ability occurs early in rats, whereas glucuronidation (of xenobiotics), and conjugation with glutathione and amino acids, only develop over about 30 days from birth. 

Simon U. E., Moritz R. F. A. and Crewe R. M. (2001) The ontogenetic pattern of mandibular gland components in queenless worker bees (Apis mellifera capensis Esch.). J. Insect Physiol. 47, 735-738. 

Many of the studies reviewed in this chapter have focused on the meroplankton. However, little is known about ontogenetic shifts in concentrations and patterns of defense in marine invertebrate larval forms.40 Further work is needed to determine if, for a wider range of species, developing larvae are capable of secondary metabolite synthesis or if defensive compounds are derived directly from adults. While a number of studies have been conducted on chemical defenses in lecithotrophic larvae of benthic invertebrates, the database is still quite small for planktotrophic larvae. Additional carefully controlled studies of aposematism in marine invertebrate larvae are also needed to determine if there is indeed a general pattern of chemical defenses in conspicuously colored larvae. 

M8. Markert, C. L., and Moller, F., Multiple forms of enzymes Tissue, ontogenetic and species specific patterns. Proc. Natl. Acad. Sci. V.S. 46, 753-763 (1959). 

McCann, D.J., Weissman, A.D., Su, T.P., 1994. Sigma-1 and sigma-2 receptors in the rat brain comparison of regional, ontogenetic and subcellular patterns. Synapse 17, 182-189. 

Hufford, L. (1995). Patterns of ontogenetic evolution in perianth diversification of Besseya (Scrophulariaceae). American Journal of Botany, 82,655-680. 

Alberch, P. and Blanco, M.J. (1996) Evolutionary patterns in ontogenetic transformation from laws to regularities , International Journal of Developmental Biology, 40, 845-58. 

---