Oligosaccharides degradation

Field M., Papac D., and Jones A. (1996), The use of high-performance anion-exchange chromatography and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry to monitor and identify oligosaccharide degradation, Anal. Biochem. 239, 92-98. 

Arnosti, C., and D. J. Repeta. 1994b. Oligosaccharide degradation by anaerobic marine bacteria Characterization of an experimental system to study polymer degradation in sediments. Limnology and Oceanography 39 1865-1877. 

Oligosaccharide Degradation Products Arising from Enzymic... 

Oligosaccharide Degradation Products Arising from Enzymic Hydrolysis of Galacto- and Gluco-mannans... 

Figure 2. Methylated oligosaccharide degradation product obtained from the incomplete Type III streptococcal antigen (9)...

Curamycin. Curamycin A, presented in Table 2, is the primary component of the culture Streptomjces curacoi (21) and preliminary chemical degradation studies (18) estabUshed it to be an oligosaccharide antibiotic. Later when the complete stmcture was assigned (17,19), the close relationship to flambamycin was evident. Curamycin A melts at 192—199°C. 

Oligosaccharide Cleavage as a Timing Device for Protein Degradation... 

The first paper on the bioactive polysaccharides from Glycyrrhiza uralensis roots was published in 1996 by Kiyohara et al. [57]. They isolated a pectic type polymer with anti-complementary and mitogenic activity that was an acidic pectin, possibly containing rhamnogalacturonan type I as part of the total structure. Degradation of the uronic acid part of the molecule decreased both types of bio activities. The neutral oligosaccharide chains were shown to retain some of the activities of the native polymer, but it was suggested that they should be attached to the acidic core to retain maximum activity. 

There is considerable evidence that a second trans-poson in the ER membrane is involved in retrograde transport of various molecules from the ER lumen to the cytosol. These molecules include unfolded or mis-folded glycoproteins, glycopeptides, and oligosaccharides. Some at least of these molecules are degraded in proteasomes. Thus, there is two-way traffic across the ER membrane. 

Presence of abnormal degradation products (eg, oligosaccharides that accumulate because of the enzyme deficiency) in urine, detectable by TLC and characterizable byGLC-MS... 

Further studies on RG-II provided structures for most of the oligosaccharides formed when it is extensively degraded with acid. A strategy... 

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