Oligonucleotides nucleic acids

Zhang, Y, Coyne, M.Y, WUl, S.G., Levenson, C.H., and Kawasaki, E.S., Single-base mutational analysis of cancer and genetic diseases using membrane bound modified oligonucleotides. Nucleic Acid Res., 19(14), 3929-3933, 1991. 

Clusel, C., Ugarte, E., Enjolras, N., Vasseur, M. and Blumenfeld, M. (1993) Ex vivo regulation of specific gene expression by nanomolar concentration of double-stranded dumbbell oligonucleotides. Nucleic Acids Res., 21, 3405-3411. 

Gannett, P. M., et al. (2002). Probing triplex formation by EPR spectroscopy using a newly synthesized spin label for oligonucleotides. Nucleic Acids Res. 30, 5328—5337. 

Deverre JR, Boutet V, Boquet D, Ezan E, Grassi J, Grognet JM (1997) A competitive enzyme hybridization assay for plasma determination of phosphodiester and phosphorothioate anti-sense oligonucleotides. Nucleic Acids Res 25(18) 3584-3589... 

Jaeske, A., Fuertste, J. P., Erdmann, V. A., and Cech, D. (1994). Hybridization-based affinity partitioning of nucleic acids using PEG-coupled oligonucleotides. Nucleic Acids Res. 22, 1880 1884. 

Johansson, H. J., and Svensson, M. A. (1995). A novel method for large-scale purification of oligonucleotides. Nucleic-acid Based Thera., San Diego, CA., 1995. 

Fluiter K, Ten Asbroek AL, De Wissel MB, Jakobs ME, Wis-senbach M, Olsson H, Olsen O, Oerum H, Baas F. In vivo tumor growth inhibition and biodistribution studies of locked nucleic acid (LNA) antisense oligonucleotides. Nucleic Acids Res. 2003 31 953-962. 

Ion-exchange chromatography (lEC) is one of the oldest HPLC modes. Today it is used for separations of small inorganic ions or of ionic biopolymers such as oligonucleotides, nucleic acids, peptides and proteins rather than in the analysis of ionic small-molecule organics, for which RPC or IPC usually offer higher efficiency and better control of selectivity and resolution. 

MacAskill A, Chemonosov A, Koval V, Lukyanets E, Fedorova O, Smith WE, Faulds K, Graham D (2007) Quantitative surface-enhanced resonance Raman scattering of phthalocy-anine labelled oligonucleotides. Nucleic Acids Res 35 e42... 

Brent, T. P. and Remack, J. S. (1988) Formation of covalent complexes between human 06-alkylguanine-DNA alkyltransferase and BCNU-treated defined length synthetic oligonucleotides. Nucleic Acids Res. 16, 6779-6788. 

Biochemical theory based on our knowledge of the rates of reaction of biological catalysts (enzymes) suggests, however, that the time from the development of protometabolism to the formation of the first oligonucleotides (nucleic acids) may in fact have required only a few thousands of years, at most a few tens of thousands of years, rather than the hundreds of millions of years implied from the geochemical data. A shorter period for the evolution of life means that there would not have been the same necessity for inordinately long periods of environmental stability and also that evolution could have been attempted in different places at different times. 

Bases, Nucleosides, Nucleotides, Oligonucleotides, Nucleic Acids, and PCR Products... 

Pon RT, Damha MJ, Ogilvie KK. Modification of guanine bases by nucleoside phosphoramidite reagents during the solid-phase synthesis of oligonucleotides. Nucleic Acids Res 13 6447-6465, 1985. 

Polushin N, Pashkova I, Efimov V. Rapid deprotection procedures for synthetic oligonucleotides. Nucleic Acids Res Symp Ser 24 49-50, 1991. 

Pichon C, Roufm MB, Monsigny M, Midoux P. Histidylated oligolysines increase the transmembrane passage and the biological activity of antisense oligonucleotides. Nucleic Acids Res 2000 28 504 512. 

Davis S, Lollo B, Freier S, Esau C 2006. Improved targeting of miRNA with antisense oligonucleotides. Nucleic Acids Res 34(8) 2294-2304. 

N. PotiCT, A. van Dorsselaer, Y. Cordio", O. Roch, and R. Bischoff, Negative electrospray ionization mass spectrometry of synthetic and chanicaUy modified oligonucleotides, Nucleic Acids Res. 22, 3895-3903 (1994). 

U. Pieles, W. ZUrcha-, M. SchSr, and H. E. Moser, Matrix-assisted laser desorption ionization time-of-flight mass spectrometry a powerful tool for the mass and sequence analysis of natural and modified oligonucleotides. Nucleic Acids Res. 21, 3191-3196 (1993). 

Burdick, A., Sciabola, S., Mantena, S., Hollingshead, B., Stanton, R., Wameke, J., et al. (2014). Sequence motifs associated with hepatotoxicity of locked nucleic acid-modified antisense oligonucleotides. Nucleic Acids Res, 42 (8), 4882-4891. 

Gibson, D. G. (2009) Synthesis of DNA fragments in yeast by one-step assembly of overlapping oligonucleotides. Nucleic Acids Res. 37, 6984-6990. 

Hansen, L. E Jensen, L. K. Jacobsen, J. P. Bis-intercalation of a homodimeric thiazole orange dye in DNA in symmetrical pyrimidine- pjulmidine-purine-purine oligonucleotides. Nucleic Acids Res. 1996, 24, 859-867. 

F. Debart, J-J. Vasseur, Y.S. Sanghvi, and P.D. Cook, Synthesis and incorporation of methyleneoxy(methylimino) (3 - 5 ) linked thymidine dimer into antisense oligonucleosides, Biomed. Chem. Lett. 2 in press (1992) Y.S. Sanghvi, J-J. Vasseur, F. Debart, and P.D. Cook, Novel strategies towards construction of non-ionic and achiral backbone in antisense oligonucleotides. Nucleic Acids Res. Synqwsium series No.27,133 (1992). 

Bennet CF, Chiang MY, Wilson-Lingardo L, Wyatt JR. Sequence specific inhibition of human type II phospholipase A2 enzyme activity by phosphorothioate oligonucleotides. Nucleic Acid Research 1994 22 3202-3209. 

Ishiyama K, Smyth GE, Ueda T et al (2004) Homo-N-oligonucleotides (N1/N9—Cl methylene bridge oligonucleotides) nucleic acids with left-handed helicity. J Am Chem Soc 126 7476-7485... 

Biolo cal/Medical Applications Detecting nucleic acids, cells, oligonucleotides nucleic acid nanochannel device nucleic acid sequencing as temperature sensor ... 

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