Oligomeric biomacromolecules

TABLE 10.3 Diagnostic tests for cooperativity of oligomeric biomacromolecules... 

The secondary structures are combined with specific geometric arrangement to form compact globular structure known as tertiary structure. The fundamental unit of tertiary structure is the domain, which is defined as a polypeptide chain or a part of a polypeptide chain that can independently fold into a stable tertiary structure (Murphy, 2001). Domains are also units of function, and often the different domains of a protein are associated with different functions. Polypeptide chains, especially of regulatory proteins, often aggregate by specific interactions to form oligomeric structures. These oligomeric proteins are said to exhibit quarternary structure. The association of proteins with other biomacromolecules to form complexes of cellular components is referred to as quinternary structure. 

As an extension of the concept of molecular adaption, the internal cavity of an oligo(m-phenylene ethynylene) helix was also anticipated to be complementary in shape to rodlike chain molecules of appropriate diameter.422 Molecular interactions of this type, while quite unlike those typical of biomacromolecules, were sought to reveal oligomeric... 

McDaniel, J.R., MacKay, J.A., Quiroz, F.G. and Chilkoti, A. (2010) Recursive directional ligation by plasmid reconstruction allows rapid and seamless cloning of oligomeric genes. Biomacromolecules, 11, 944-952. 

G. Lligadas, J. C. Ronda, M. Galia and V. Cadiz, Bionanocomposites from renewable resources Epoxidized linseed oil-polyhedral oligomeric silsesquiox-anes hybrid materials . Biomacromolecules, 2006,12, 3521-6. 

Viswanathan K, et al. (2010) Protease-Catalyzed Oligomerization of Hydrophobic Amino Acid Ethyl Esters in Homogeneous Reaction Media Using L-Phenylalanine as a Model System. Biomacromolecules. 11 p. 2152-60. 

Kannan RY, Salacinski HJ, De Groot J, Clatworthy 1, Seifalian AM, et al. The antithrom-bogenic potential of a polyhedral oligomeric silsesquioxane (POSS) nanocomposite. Biomacromolecules January 2006 7(l) 215-23. 

Ohara H, Onogi A, Yamamoto M, Kobayashi S (2010) Lipase-catalyzed oligomerization and hydrolysis of alkyl lactates direct evidence in the catalysis mechanism that enantioselection is governed by a deacylation step. Biomacromolecules 11 2008-2015... 

Ohara H, Nishioka E, Yamaguchi S, Kawai F, Kobayashi S (2011) Protease-catalyzed oligomerization and hydrolysis of alkyl lactates involving L-enantioselective deacylation step. Biomacromolecules 12 3833-3837... 

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