Oleaginous yeasts

Production of Functional y-Linolenic Acid (GLA) by Expression of Fungal A12- and A6-Desaturase Genes in the Oleaginous Yeast Yarrowia lipolytica... 

Mortierella alpina oleaginous yeast Yarrowia Upolytica. 

HaU, M.J., and Ratledge, C., Lipid accumulation in an oleaginous yeast (Candida 107) growing on glucose under various conditions in a one- and two-stage continuous culture, Appl. Environ. Microbiol. 1977, 33, 577-584. 

Evans, C.T. Ratledge, C. Partial purification and properties of pyruvate kinase and its regulatory role during lipid accumulation by the oleaginous yeast Rhodosporidium toruloides CBS 14. Can. J. Microbiol., 31, 479-484 (1985)... 

Genetic manipulation of oleaginous yeast will not only further improve the yields and feasibility of single-cell oil production processes but also the generation of novel lipids with high value. Often-named examples are fatty acids similar to natural products like cocoa butter or fish oil, which are becoming... 

Hu, C., Zhao, X., Zhao, J., Wu, S. et al (2009) Effects of biomass hydrolysis by-products on oleaginous yeast Rkodosporidium toruloides. Bioresour. Technol, 100, 4843-4847. 

Papanikolaou, S. and Aggelis, G. (2011) Lipids of oleaginous yeasts. Part I biochemistry of single cell oil production, Eur. J. Lipid Sci. Technol, 113, 1031-1051. 

Tai, M. and Stephanopoulos, G. (2013) Engineering the push and pull of lipid biosynthesis in oleaginous yeast Yarrowia lipolytica for biofuel production. Me tab. Eng., 15, 1-9,... 

Haddouche, R., Poirier, Y., Delessert, S. et al. (2011) Engineering polyhydroxyalkanoate content and monomer composition in the oleaginous yeast Yarrowia lipolytica by modifying the 6-oxidation multifunctional protein. Applied Microbiology and Biotechnology, 91(5), 1327-1340. 

LycoRed, an Israeli company, obtains lycopene from Tangerine tomatoes, which are especially cultivated for this purpose. Another source of lycopene is the biomass from fermentation of the fungus Blakeslea trispora, which is extracted with isobutyl acetate and crystallised. [82] DuPont and Microbia Inc. (now DSM) developed processes for the production of canthaxanthin with the aid of the recombinant oleaginous yeast Yarrowia lipolytica. [83]... 

Figure 9.1 Idealized pattern of lipid accumulation in an oleaginous yeast or mould growing...

Table 9.2 Lipid content and fatty acid profiles of oleaginous yeasts ...

Table 9.2 lists the oleaginous yeasts currently known to produce 20% or more lipid together with their major component fatty acids. It will be seen that this is a relatively short list consisting of less than 30 species including the border-line ones. The total number of yeast species is 590 (Barnett et al., 1990), so it can be instantly appreciated that oleaginicity is not a widespread characteristic amongst yeasts even though many of the species have yet to be fully explored for lipid accumulation. 

Boulton, C.A. and Ratledge, C. (1983a) Use of transition studies in continuous cultures of Lipomyces s tar key i, an oleaginous yeast, to investigate the physiology of lipid accumulation. J. Gen. Microbiol. 129, 2871-2876. 

Browne, H.M., Dowsett, A.B., Gibson, R.K. and Peberdy, J.F. (1987) The isolation and regeneration of protoplast from Lipomyces starkeyi an oleaginous yeast. J. Microbiol. Methods 6, 153-165. 

Davies, R.J., Holdsworth, J.E. and Reader, S.L. (1990) The effect of low oxygen uptake rate on the fatty acid profile of the oleaginous yeast, Apiotrichum curvatum. Appl. Microbiol. Biotechnol. 33, 569-573 (erratum (1991) 34, 832-833). 

Evans, C.T. and Ratledge, C. (1983) A comparison of the oleaginous yeast, Candida curvata, grown on different carbon sources in continuous and batch culture. Lipids 18, 623-629. 

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