Ofloxacin Cyclosporine

Drug interactions The effect of antacids and cations on the absorption of these agents was considered above. Ciprofloxacin, ofloxacin and enoxacin can increase the serum levels of theophylline by inhibiting its metabolism. They also may raise levels of warfarin, caffeine and cyclosporine. Cimetidine interferes with the... 

Wynckel A, Toupance O, Melin JP, David C, Lavaud S, Wong T, Lamiable D, Chanard J. Traitement des legionelloses par ofloxacine chez le transplante renal. Absence d interference avec la ciclosporine A. [Treatment of legionellosis with ofloxacin in kidney transplanted patients. Lack of interaction with cyclosporin A.] Presse Med 1991 20(7) 291-3. 

Patients who received bone marrow [267] and heart transplants [268] did not show any evidence of nephrotoxicity when receiving ciprofloxacin. Contrary to previous preliminary findings [253,269], more recent data suggest lack of relevant pharmacokinetic interaction of ciprofloxacin with cyclosporine[268]. Similar preliminary claims of norfloxacin [270], ofloxacin [271], and pefloxacin-cyclosporine [272] interactions have been made. 

Clinically important, potentially hazardous interactions with alfentanil, aminophylline, amisulpride, amoxicillin, ampicillin, anticonvulsants, astemizole, atorvastatin, benzodiazepines, bromocriptine, buprenorphine, bupropion, carbamazepine, cilostazol, ciprofloxacin, cisapride, clindamycin, colchicine, cyclosporine, dasatinib, digoxin, dihydroergotamine, diltiazem, disopyramide, enoxacin, eplerenone, ergotamine, eszopiclone, everolimus, fluconazole, fluoxetine, fluvastatin, gatifloxacin, HMG-CoA reductase inhibitors, imatinib, itraconazole, ketoconazole, lomefloxacin, lorazepam, lovastatin, methadone, methylprednisolone, methysergide, midazolam, mizolastine, moxifloxacin, nitrazepam, norfloxacin, ofloxacin, paroxetine, pimozide, pravastatin, quinolones, ranolazine, repaglinide, rupatadine, sertraline, sildenafil, simvastatin, sparfloxacin, sulpiride, tacrolimus, terfenadine, triazolam, troleandomycin, vardenafil, verapamil, vinblastine, warfarin, zaleplon, zolpidem, zuclopenthixol... 

Cellulose Based Drug Delivery Synthetic Nanoparticles, Microsphere, Tablet Excipients, Protein Based Drug Delivery, Spray Drying Acetaminophen, Cyclosporine A, Norfloxacin, Ofloxacin, Ciprofloxacin, Gatifloxacin, Levofloxacin, Protein delivery and purification... 

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