Of eating disorders

MC4R for feeding behaviour, targeting one or both of these recqDtors in addition to understanding the complex cross-talk within the CNS may lead to the development of melanocortin based therapeutics for the treatment of eating disorders [5]. 

Samanin, R and Grignaschi, G (1996) Role of 5-hydroxytryptamine receptor subtypes in satiety and animal models of eating disorders. In Drug Receptor Subtypes and Ingestive Behaviour (Eds Cooper, SJ and Clifton, PG), Academic Press, London, pp. 39-58. 

The studies reviewed above focused on constructs that closely relate to DSM syndromes. However, the field of eating disorders is more complex. For example, Tylka and Subich (2003) emphasized a distinction between behavioral or symptomatic indicators, such as binging and purging, and... 

K. P. (1998). The interview for the Diagnosis of Eating Disorders-IV Application to DSM-IV diagnostic criteria. Psychological Assessment, 10, 41-48. 

Tylka, T. L.,. Subich, L. M. (2003). Revisiting the latent structure of eating disorders Taxometric analyses with nonbehavioral indicators. Journal of Counseling Psychology, 50, 276-286. 

Glandular functions of eating-disorder patients slow down as a result of... 

There are data to confirm and reject the association of the Cys23Ser S-HT and the Gly22Ser 5-HTj receptor variants, characterized in vitro by reduced agonist potency, with phenotypes such as intractable suicidal ideation (98), ADHD (100), alcohol dependence, and schizophrenia (98,99,109-116). While the -1348 A/G polymorphism of the S-HT receptor has been associated with the negative symptoms of schizophrenia, other studies of eating disorders appear to be equivocal. A body of evidence is available, however, that S-HT variants may be associated with psychotic symptoms in Alzheimer s patients (94,100,117,118). 

Although evaluation of obesity is important, the elucidation of patterns of eating behavior is the critical component in the assessment of eating-disordered obese patients. Unfortunately, it is just this aspect of the evaluation that is most often neglected in treatment programs that too narrowly focus on weight reduction. If a careful history is obtained, then BED is not difficult to diagnose. 

Birmingham CL, Beumont PJV, Crawford R, et al. Medical Management of Eating Disorders A Practical Handbook for Healthcare Professionals. Cambridge, UK Cambridge University Press, 2004. 

Roerig JL, Mitchell JE, Myers TC, et al. Pharmacotherapy and medical complications of eating disorders in children and adolescents. Child Adolesc Psychiatr Clin North Am 2002 11(2) 365-385. 

Unlabeled Uses Treatment of eating disorders, postconcussional syndrome unresponsive to other treatments... 

Ellison, A.R., and Fong, J., Neuroimaging in eating disorders. In Hoek, H.W, Treasure, J.L., and Katzman, M.A. eds. Neurobiology in the Treatment of Eating Disorders. Chichester John Wiley... 

Morley, J.E. and Blundell, J.E. (1988) The neuroblological basis of eating disorders some formulations. Biol Psychiatry 23 53-78. 

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