Occlusal - Salicylic acid

Oasil - Meprobamate Obaron - Benzbromarone Obe-Del Phendimetrazine tartrate Obepar - Phendimetrazine tartrate Obesan - Phendimetrazine tartrate Obestat Phenylpropanolamine HCI Obestin - Phentermine HCI Obetrol - Dextroamphetamine sulfate Obex-LA Phendimetrazine tartrate Obezine Phendimetrazine tartrate Oblioser - Methaqualone Obotan - Tanphetamin Obsidan Propranolol HCI Obstiiax - Bisacodyl Obstilex - Oxyphenisatin acetate Oby-Trim Phentermine HCI Occlusal - Salicylic acid Ocelina - Metampicillin sodium Oceral Oxiconazole nitrate Octapressin Felypressin Octtcair - Hydrocortisone Octicair - Neomycin Octicair Polymyxin Octinum Isometheptene Octocaine Lidocaine... 

Propylene glycol is used extensively in topical preparations because it is an excellent vehicle for organic compounds. It has been used alone as a keratolytic agent in 40-70% concentrations, with plastic occlusion, or in gel with 6% salicylic acid. 

Propylene glycol is used under polyethylene occlusion or with 6% salicylic acid for the treatment of ichthyosis, palmar and plantar keratodermas, psoriasis, pityriasis rubra pilaris, keratosis pilaris, and hypertrophic lichen planus. 

Verrucae are self-limiting but can be very serious in the immunosuppressed. Treatment is primarily cosmetic but also prevents further dissemination. Most verrucae lesions resolve spontaneously after several months to years therefore therapy should be conservative. Because the lesions are localized to the epidermis, most treatments are limited to this level and should not result in scarring. Benign treatments include topical applications of irritants salicylic acid and lactic acid, applied under an occlusive barrier, can be purchased over the counter. More advanced treatment modalities include cryotherapy, surgical removal, or electro-or chemical cautery. Neither of these cautery methods is suitable for lesions on the lid margin because of the risk to the ocular surfece. 

At concentrations above 2% salicylic acid has a keratolytic effect, causing the keratin layer of the skin to shed. Keratolysis is achieved by increasing the hydration of the stratum corneum, softening the cells and facilitating dissolution of the intracellular cement that bonds the cells together so that they separate and detach (desquamate). Moisture is essential to this process and is provided by either the water in the formulation or the occlusive effect produced by its application to the skin. 

After leaving the solution to rest for 24 hours and filtering it, UV exposure was what made it effective Solutions not exposed to UV did not appear to work. The skin was also prepared by UV exposure, and the solution was applied five times, leaving each coat to dry before the next application. Urkov then applied an occlusive mask. This mask allowed the superficial layers to hyperhydrate by blocking transepi-dermal water loss (TEWL). The hyperhydration dissolved the salicylic acid that would have precipitated on the skin without occlusion and could not have penetrated, as only the acids in solution can readily penetrate the skin barrier. He then applied zinc stearate powder (which is antiseptic and anti-inflammatory). The erythema subsided in 5-6 days and exfoliation was superficial. The solution can be kept in the fridge for 10 days. 

One of the hypotheses for the development of vascular occlusion that precedes proliferative diabetic retinopathy is that disturbances in the thrombocyte aggregation lead to leukostasis and formation of microthrombosis in the retinal capillaries. Consequently, attention has been focused at treating diabetic retinopathy with inhibitors of thrombocyte aggregation. However, a prospective study has shown that acetyl salicylic acid does not reduce the development of diabetic retinopathy. Additionally, this treatment does not increase the risk of developing complications such as vitreous hemorrhage. This is important evidence since inhibitors of thrombocyte aggregation are often used to reduce the risk of the development of the macrovascular complications of the disease [12]. 

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