O -alkyl/cycloalkyl

Tabun is the best known example of the family of O-alkyl/cycloalkyl /V,/V-dialkylphosphoramidocyan-idates. Its fragmentation is rather different, compared... 

In an analogous manner to the behavior of the tabun family, branching of the alkyl/cycloalkyl chain does not have a large influence, and mass spectra of a few compounds are generally sufficient for the primary identification of VX family members. A series of El mass spectra of O-alkyl/cycloalkyl 5-2-dialkyl aminoethy 1 alkyl(ethyl, isopropyl, or propyl)phosphonothiolates has been recorded and contributed to the OPCW Analytical Database. 

Fig. 19 Synthesis and cyclative cleavage of 2,4,6-trisubstituted pyrimidines using microwave-assisted solid-phase protocol. Reagents and conditions a DMF, camphorsul-phonic acid, MW 80 °C, 30 min, open vessel b EtONa, EtOH/THF (4/1), MW 130 °C, to min, closed vessel. Y = O, NEt2 R = Me, i-Pr R = Et R" = H, alkyl, cycloalkyl, aryl, benzyl R" = H, Me, Et...

Some structure-activity relationships of a further developed R4, R5 alkyl/cycloalkyl series (2a-o, Fig. 10, Table 1) were also investigated. This study [69] revealed structural features that favored allosteric enhancing activity, such as benzoyl lipophilic substitution and thiophene 4-alkyl substitution, while other features, such as thiophene 5-bulky substitution, favored antagonistic properties. Upon further analysis, a... 

O-Alkyl (less than or equal to CIO, including cycloalkyl) alkyl (methyl, ethyl, propyl, or isopropyl) phosphonofluoridates, or... 

Dialkyl peroxides (1), R-O-O-R (R and R are = or primary, secondary, tertiary alkyl, cycloalkyl, aralkyl and heterocyclic radicals Homolytic decompn when heated or irradiated with prodn of free radicals for org synthesis difficult to hydrolyze and reduce rearrangement crosslinking and polymerization polymeric peroxides are thick liqs or amorph wh powds used as polymerization catalysts Primary radicals are unstable, lowest members such as dimet peroxide are shock sens and dangerous expls sensitivity lessens with increasing mw polymeric peroxides (copolymers of olefins and Oj) explode on heating... 

Alternatively, UV irradiation is used. Unactivated alkyl, cycloalkyl and aryl compounds, as well as o-carboranes participate . Yields for the formation of methyl-and ethylmercurials from the carboxylates are 66 and 68 %, respectively " ... 

R = H, aiky, aryi, OH, 0-aikyi, 0-aryi, Ci, Br, CF3, C02-alkyl, etc. R = H, alkyl, cycloalkyl, aryl, benzyl R = alkyl, aryl, CO2-alkyl, 0-alkyl R = alkyl, aryl, O-alkyl, NH2, NR2 solvent acetone, EtOH, MeN02, AcOH, CHCI3... 

Nitrogen Mustard 1 [CAS 538-07-8] Nitrogen Mustard 2 [CAS 51-75-2] Nitrogen Mustard 3 [CAS 555-77-1] O-Alkyl (H or less than or equal to CIO, including cycloalkyl) S-2-dialkyl (Me, Et, n-Pr or i-Pr)-aminoethyl alkyl (Me, Et, n-Pr or i-Pr) phosphonothiolate and corresponding alkylated or protonated salts... 

Capping of terminal hydroxyl groups OH, CH,X " -HY CHg X CH3 X-Y = R-O-SOj-O R, R-SOj-halogen, R-CO-halogen, R-CO-O-CO-R R-halogen (15). R=alkyl, cycloalkyl, aryl, arylalky PPO blcKk copolymers can be formed by polycondensation of aromatic dicarboxylic acids, aromatic diamines, etc. Improving PCM s performances... 

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