Nurses’ Health Study colon cancer

GIOVANNUCCI E, STAMPFER M J, COLDITZ G A, HUNTER J, FUCHS C, ROSNER B A, SPEIZER F E and WILLETT w c (1998) Multivitamin use, folate, and colon cancer in women in the Nurses Health Study , Ann Intern Med, 129, 517-24. 

A study on diet and colon cancer was reported by W. Willett s group (Willett et at., 1990) (Table 11.3). The study examined various components of the diet, such as fiber, fat, and meat. The fiber component was divid into cereal fiber and fruit fiber. The fat component was divided into meat fat, dairy fat, saturated fat, and unsaturated fat. The meat component was divided into beef, pork, and lamb, and into rare versus well-done Styles of cooking. The body mass index, as defined in the Obesity chapter, was also recorded. The study was part of the Nurses Health Study Cohort, which was inibated in 1976 and involved 121,700 female nurses. Every 2 years, the nurses filled in a questionnaire that asked about various risk factors for disease. The questionnaire asked, for example, about 61 foods and their frequency In the diet. The foods were chosen to allow epidemiologists to make broad statements regarding the component nutrients. 

The two largest studies, Nurse s Health Study (NHS) and Health Professional Follow-up Study (HPFS), were also examined together for the relationship of vitamin E and colon cancer but the findings do not provide consistent support of an inverse association between supplemental vitamin E and colon cancer risk (26). 

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