Nucleophiles in nucleophilic substitution reactions

Heterocycles as nucleophiles in nucleophilic substitution reactions by electron transfer 03CRV899. 

Because of the lone pair on the nitrogen, amines are both bases and nucleophiles. Amines react as nucleophiles in nucleophilic substitution reactions, in nucleophilic acyl substitution reactions, in nucleophilic addition-elimination reactions, and in conjugate addition reactions. 

The use of anion-exchangers as the source of nucleophiles in nucleophilic substitution reactions has been referred to (Chapter 12). Brown and Jenkins (1976) and Regen (1975, 1976, 1977) have developed a triphase-catalysis method for carrying out such nucleophilic substitution reactions. The resin in these reactions acts as a polymer-bound phase-transfer catalyst. Quaternary ammonium groups that were introduced into the resin contained large alkyl groups to act as the linked phase-transit catalyst. 

Amines react as nucleophiles in nucleophilic substitution reactions, in nucleophihc addition-eUmination reactions, and in conjugate addition reactions. 

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See also in sourсe #XX -- [ ]

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