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Alcohols in nucleophilic substitution reactions

But we want to use alcohols in nucleophilic substitution reactions because they are easily made. The simplest answer is to protonate the OH group with strong acid. This will work only if the nucleophile is compatible with strong acid, but many are. The preparation of f-BuCl from f-BuOH simply by shaking it with concentrated HC1 is a good example. This is obviously an SnI reaction with the t-butyl cation as intermediate. [Pg.430]


See also in sourсe #XX -- [ Pg.280 ]




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Alcohol nucleophilic reactions

Alcohol substitution reaction

Alcohols nucleophiles

Alcohols nucleophilic substitution

Alcohols nucleophilic substitution reactions

Alcohols nucleophilicity

In nucleophilic substitutions

Nucleophile alcohols

Nucleophiles in nucleophilic substitution reactions

Nucleophiles in substitution reactions

Nucleophiles substitution reactions

Nucleophilic alcohols

Nucleophilic substitution reactions nucleophiles

Substituted alcohols

Substitution reactions nucleophile

Substitution reactions nucleophilic

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