Northern Regional Research Laboratory

Xanthan Gum. As a result of a project to transform agriculturally derived products into industrially usefiil products by microbial action, the Northern Regional Research Laboratories of the USDA showed that the bacterium TCanthomonas campestris - noduces a polysaccharide with industrially usefiil properties (77). Extensive research was carried out on this interesting polysaccharide in several industrial laboratories during the eady 1960s, culminating in commercial production in 1964. 

There are currentiy no commercial producers of C-19 dicarboxyhc acids. During the 1970s BASF and Union Camp Corporation offered developmental products, but they were never commercialized (78). The Northern Regional Research Laboratory (NRRL) carried out extensive studies on preparing C-19 dicarboxyhc acids via hydroformylation using both cobalt catalyst and rhodium complexes as catalysts (78). In addition, the NRRL developed a simplified method to prepare 9-(10)-carboxystearic acid in high yields using a palladium catalyst (79). 

G-21 Dicarboxylic Acids. C-21 dicarboxylic acids are a mixture of predominately 5-(6)-carboxy-4-h.exyl-2-cycloliexene-l-octanoic acid, 5-isomer [42763-47-3] and 6-isomer [42763-46-2]. C-21 dicarboxylic acids were first described at the Northern Regional Research Laboratory in Peoria, Illinois (89). 

Northern Regional Research Laboratory (NRRL), now the National Center for Agricultural Utilization Research. 

Northern Regional Research Laboratory, Bureau of Agricultural and Industrial Chemistry, Agricultural Research Administration, U. S. Department of Agriculture, Peoria, Illinois... 

NRRL Northern Regional Research Laboratories, Agricultural Research Service, USDA, 1815 N. University Street, Peoria, IL 61604, USA... 

Northern Regional Research Laboratory, Northern Utilization Research and Development Division, Agricultural Research Service,... 

Cephalotaxus is a genus of plum yew natural to Eastern Asia, although it is now cultivated in many parts of the world (94). There are about seven species and most have been examined for alkaloids, which have been obtained from all parts of the plants. Since the alkaloidal extracts were reported in 1969 to exhibit antitumor activity (95), an intense investigation of the Cephalotaxus alkaloids has followed (8, 9). Most of the isolation work, structural elucidation, and pharmacological assay has come from the Northern Regional Research Laboratory in Illinois (5). 

Unpublished data from studies of levoglucosan production, by I. A. Wolff, D. W. Olds and O. E. Hilbert at the Northern Regional Research Laboratory. 

Figure 3-1 Component Amino Acids of Proteins Joined by Peptide Bonds and Character of Side Chains. Source From Northern Regional Research Laboratory, U.S. Department of Agriculture.

John Edward Hodge, a distinguished carbohydrate chemist and prominent member of the African-American community, died of cancer on January 3,1996. John was internationally known, primarily for his work in the area of nonenzymatic browning (the Maillard reaction), which was carried out during his years of service at the United States Department of Agriculture s Northern Regional Research Laboratories in Peoria, Illinois, where he served on the staff for more than 40 years. 

This writer is deeply indebted to and acknowledges the following persons for their help in the preparation of this article Mrs. Dorothy Johnson (sister) of Kansas City, Missouri, for a number of helpful discussions relative to John s childhood and early life Mrs. Justina Hodge (widow), of Peoria, Illinois, for access to archival materials and Dr. William Doane (colleague) of Peoria, Illinois, for detailed information on John s professional life while he was on the staff at the Northern Regional Research Laboratories in Peoria. 

In early 1941, Dr. Jeanes moved back to Illinois, this time to Peoria, just three months after the opening of the U.S. Department of Agriculture s Northern Regional Research Laboratory (NRRL, later NRRC, and now the National Center for Agricultural Utilization). She continued to work there even after her retirement in 1976. Her more than 35 years of research at NRRL resulted in two major scientific and industrial developments, dextran and xanthan, and these are described in more than 60 publications, 24 presentations, and 10 patents. 

Northern Regional Research Laboratories Northern Utilization Branch, Agricultural Research Service, U.S.D.A., Peoria, IL, U.S.A. NRRL... 

It was perhaps inevitable that the Oxford team would turn to their colleagues in the USA for assistance, since America was rich and still at peace. Florey and Heatley travelled to the USA in July 1941 with samples of Penicillium notatutm. Almost at once, they received very constructive help from Charles Thom of the Department of Agriculture, the scientist who had helped with the identification of the mould some ten years previously. He passed them on to the USDA s Northern Regional Research Laboratory in Peoria, Illinois, which had considerable expertise with fermentation technology. They quickly established that the mould could be grown more effectively on com steep liquor... 

Floss, H. G., lecture series presented at USDA Northern Regional Research Laboratories, Peoria, 111., May, 1969. 

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