Nonsense correlation

Another effect is known as nonsense correlation, and is observed because inevitably we do not measure all the variables that can effect a method. If there is a latent or lurking variable that causes an effect in... 

Yule, G. Why do we sometimes get nonsense-correlations between time-series -a study in sampling and the nature of time-series. Journal of the Royal Statistical Society, 89 (l) l-63, 1926. 

With respect to correlation, the behaviour of the hydrogen molecule studied in a subminimal FSGO basis set is still more striking than the one observed in a minimal basis set. By symmetry arguments, the single FSGO which describes the electron pair of the hydrogen molecme is centred at the middle of the H-H bond. As the intemuclear distance increases and ultimately when the molecule dissociates, such a description would lead to a physical nonsense. Indeed, at the dissociation limit, this would correspond to two protons (2H ) and an isolated pair of electrons (2e ). 

Low levels or absence of adenosine deaminase (ADA) is associated with one form of severe combined immunodeficiency disease (SCID) characterized by B-andT-lymphocyte dysfunction due to toxic effects of deoxyadenosine (HI9). Most patients present as infants with failure to thrive, repeated infections, severe lymphopenia, and defective cellular and humoral immunity. Disease severity is correlated with the degree of deoxyadenosine nucleotide pool expansion and inactivation of S-adenosylhomocysteine hydrolase in red blood cells. Up to now, more than 40 mutations have been identified (A4, H20, S5, S6). The majority of the basic molecular defects underlying ADA deficiency of all clinical phenotypes are missense mutations. Nonsense mutations, deletions ranging from very large to single nucleotides, and splicing mutations have also been reported. It is likely that severe... 

The arguments in favor of forebrain mechanisms in dreaming presented here are designed in part to counter the widespread misperception that activation-synthesis regards REM sleep as the exclusive correlate of dreaming, that the forebrain in sleep does only what the brain stem tells it to do, and that dreaming is entirely nonsensical due to the... 

In Chapter 5 we saw how the calculation of the 95 per cent Cl for the mean can lead to nonsensical results if the data deviate severely from a normal distribution. This requirement for a normal distribution also applies to the t- tests, analyses of variance and correlation that we met in Chapters 6-14. These procedures are termed parametric methods and are quite robust, so moderate non-normality does little damage, but in more extreme cases, some pretty dumb conclusions can emerge. This chapter looks at steps that can be taken to allow the analysis of seriously non-normal data and also of ordinal scale data. 

Because of the difference in prevalence of inhibitors in hemophilia B and hemophilia A, it has been postulated that there is a correlation between mutation type and inhibitor risk (6). Of the patients with gross deletion, nonsense, or frameshift mutations, 11% developed inhibitors compared with 0% and 0.36% of patients with hemophilia B with mis-sense or other mutations. 

When working with pseudo-receptors, and in general with quantitative structure-activity relationships (QSAR) of any dimension, a word of caution is necessary with respect to the biological data that is used. These should preferably constitute binding affinities from a single laboratory, a prerequisite which is also true for all QSAR studies. Since the receptor models simulate interaction events (AH) in a highly simplihed manner, the experimental data which are combined with them in a correlation analysis mnst be as close to the molecular level as possible. It is therefore nonsense to correlate the calculated interaction energies... 

The second conclusion can be accepted, since it follows from the pairing of the spins, but the first conclusion is just absurd. Such nonsense is admitted by the Hartree-Fock method. In this chapter, we will ponder how can we introduce a correlation of electronic motions. 

To make a correlation of protein bands and genes, nonsense mutants of 029 were utilized. The protein affected by a nonsense mutation should disappear from its normal position in Ae patterns obtained upon electrophoresis of extracts of mutant-infected cells on SDS-polyacrylamide gels. The proteins specified by thirteen of the eighteen genes known in 029 have been identified. These proteins are named with a p before the letter designating the gene (Fig. 3). 

Thus we see the collision and interaction of two worlds the completely legalized, official world shaped by ranks and uniforms, vividly portrayed in the dream of life in the capital, and the world where all is funny and nonserious, where only laughter is taken seriously. The nonsense and absurdities introduced by this world seem, on the contrary, to be the genuine, unifying inner source of the other, external world. This is the merry absurdity of folk sources, which contain the multitude of speech correlations accurately recorded by Gogol. 

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