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Non-viral gene therapy

Li SD, Huang L (2006) Gene therapy progress and prospects non-viral gene therapy by systemic delivery. Gene Ther 13 1313-1319... [Pg.62]

Hebert E. Improvement of exogenous DNA nuclear importation by nuclear localization signal-bearing vectors a promising way for non-viral gene therapy Biol Cell 2003 2 95(2) 59-68. [Pg.315]

Taira K, Kataoka K, Niidome T (eds) (2005) Non-viral gene therapy gene design and delivery. Springer, Tokyo... [Pg.43]

Ewert K, Ahmad A, Evans H, Safinya CR (2005) Cationic lipid-DNA complexes for non-viral gene therapy relating supramolecular structures to cellular pathways. Expert Opin Biol Ther 5 33-53... [Pg.222]

In the case of non-viral gene therapy, efficacy depends on the intrinsic properties of plasmid DNA and the delivery system used. The topology of plasmid DNA is known to affect its in-vitro transcriptional efficiency. Higher gene expression... [Pg.125]

Our studies support the hypothesis that cardiac cell membrane lesion sealing with CSIL result in preservation of myocardial viability, as determined by function, histochemistry, and ultra-structural morphology. There is a time response to myocardial preservation with CSIL therapy. Early CSIL intervention after the onset of ischemia resulted in almost complete myocardial recovery (18). Even when the intervention was initiated at 20 min of global ischemia, myocardial preservation was still greater than that seen in hearts with IgG-L or placebo treatment. There is also a dose response to CSIL therapy. Sufficient concentration of CSIL is essential to achieve optimal cell membrane lesion sealing (I9).Therefore, CSIL therapy may find therapeutic applications in preservation of myocardial viability and efficient non-viral gene therapy. [Pg.316]

Thomas M, Klibanov A M (2003). Non-viral gene therapy polycation-mediated DNA delivery. Appl. Microbiol. Biotechnol. 62 27-34. [Pg.1052]

The field of non-viral gene therapy has recently gained increased interest (75). It is widely believed that non-viral gene therapy can overcome some problems inherent to cm -rent viral-based therapies, including immune and toxic reactions as well as the potential for viral recombination (76). The Pluronic block copolymers, as one class of non-ionic polymers, have proven to be useful elements to the polyplexes for gene therapy applications. Furthermore, Pluronic block copolymers themselves appear to be very valuable for gene dehvery... [Pg.596]

Laporte LD, Rea JC, Shea LD (2006) Design of modular non-viral gene therapy vectors. Biomaterials 27 947-954... [Pg.153]

Ledley FD. Non-viral gene therapy. Curr Opin Biotechnol 1994 5 626-36. [Pg.414]

Li, S., Huang, L. 2000. Non-viral gene therapy Promises and challenges. Gene Ther. 7 31—34. [Pg.389]

Replacement of the cw-double bonds of dioleoylphosphatidylethanolamine DOPE (111) with triple bonds produces analogues (112)-(114), that are highly-transfecting cationic liposomes for non-viral gene therapy. ... [Pg.140]

HoUaday, C. A., O brien, T., and Bandit, A. 2009. Non-viral gene therapy for myocardial engineering. Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology, 2,232-248. [Pg.366]


See other pages where Non-viral gene therapy is mentioned: [Pg.148]    [Pg.368]    [Pg.355]    [Pg.653]    [Pg.657]    [Pg.241]    [Pg.1511]    [Pg.615]    [Pg.638]    [Pg.3]    [Pg.5]    [Pg.7]    [Pg.9]    [Pg.11]    [Pg.13]    [Pg.15]    [Pg.15]    [Pg.17]    [Pg.365]    [Pg.789]    [Pg.790]    [Pg.807]    [Pg.75]    [Pg.242]    [Pg.256]   
See also in sourсe #XX -- [ Pg.596 ]




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