Nitrogen tetraoxide

To prevent oxidation of nitrous oxide to nitrogen tetraoxide, excess ascorbic acid must be used. Douglas et al (1978) has reviewed the numerous literature reports on ascorbic acid inhibition of nitrosamine formation in amine-nitrite systems. 

Nitrogen oxides, which are mainly released from industrial stacks, include nitrous oxide (N2O), nitric oxide (NO), nitrogen dioxide (NO2), nitrogen trioxide (N2O3), nitrogen tetraoxide (N2O4),... 

Sawyer, R. F., The Homogeneous Gas-Phase Kinetics of Reactions in Hydrazine-Nitrogen Tetraoxide Propellant System, Ph.D. Thesis, Princeton University, 1965. 

An alternative procedure for the protection of L-sorbose (25), followed by oxidation at C-l and cyclization of the product to L-ascorbic acid, was developed by Hinkley and Hoinowski.257 L-Sorbose (25) was converted into methyl a-L-sorbopyranoside (37) by treatment with methanol and hydrogen chloride.258 Glycoside 37 was then oxidized with air in the presence of a suspension of platinum oxide in aqueous sodium hydrogencarbonate solution at 60°, to afford methyl ot-L-xylo-2-hexulopyranosidonic acid (38), which, when heated in hydrochloric acid, was converted into L-ascorbic acid (1), presumably by way of L-xy/o-2-hexulosonic acid (see Scheme 5). Acid 38 has also been prepared by oxidation of 37 with nitrogen tetraoxide.259,280 Yields were not reported for this reaction sequence, and it appears to offer no potential... 

Two methods by which D-glucofuranurono-6,3-lactone (63) has been synthesized are shown in Scheme 9. The oxidation of starch to oxidized starch (64) has been described by a number of workers. Heyns and Graife338 were able to obtain 50-55% yields of 64 by oxidation with nitric acid plus nitrogen tetraoxide. From 64, D-glucofuran-... 

Consideration of the absorption spectra of these two gases leads to the conclusion that the primary photochemical decomposition in nitrogen peroxide, which consists of nitrogen peroxide and nitrogen tetraoxide, is due to the tetraoxide constituent. 

C graphite 7782-42-5 2590E+09 16.000 2749 N204 nitrogen tetraoxide 10544-72-6 4.960E+08 30.080... 

When exposed to air, nitric oxide may be converted to nitrogen dioxide or nitrogen tetraoxide, both of which are highly toxic. Conversion is slower at concentrations below 1 ppm. Other contaminants, such as ozone in the air, expedite the conversion process. 

Effects similar to those seen on acute exposure are also seen chronically. In addition, if the compound is converted to nitrogen dioxide or nitrogen tetraoxide, toxicities associated with these compounds can also be observed. 

Nitrogen tetraoxide is formed by pressurizing liquid nitrogen dioxide. It is a gas at normal temperature and pressure, and is used in the manufacture of explosives and rocket fuels. Nitrogen tetraoxide is used as a catalyst in oxidation reactions and in many other industrial applications. It is also a component of nitric and sulfuric acid. 

Nitrogen tetraoxide is absorbed through the respiratory system and reacts with blood, reducing fluid levels, inducing massive pulmonary edema, and a severe reduction in hemoglobin levels. 

The inhalation LC50 is 315 ppm in rabbits. Nitrogen tetraoxide as a liquid can cause severe burns from even brief contact with the skin or eyes. 

Exposure to nitrogen tetraoxide in the missile industry can lead to symptoms identical to those from nitrogen dioxide. Medical assistance should be sought immediately after any inhalation exposure, however small. If eyes or skin are exposed these should be well rinsed with water. 

Nitrogen Tetraoxide, Pages 245-246, Samantha E. Gad SummaryPlus Full Text + Links PDF (58 K)... 

NItrobutanol (2-) Nitrogen Tetraoxide Nltrom ethane Octadecyl Alcohol Ozone... 

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