Nitro triazoles

An analogous reaction with 2, 3/,5 -triacetyluridine and mesitylenesulfonyl-3-nitro-triazole or triisopropylbenzenesulfonyl-3-nitrotriazole proceeds with the same high yield. Treatment of the nitrotriazolyl nucleoside with ammonia leads to 2, 3, 5 -triacetyl-cytidine.[194]... 

This shows that the combination of diphenylphosphate and arylsulfonyl-3-nitro-triazole is a powerful phosphorylating agent in pyridine solution. 

The influence of different modifiers on extraction efficiency with a concentration of 4 mol% is pointed out in diagram 2. With pure supercritical carbon dioxide,only pentaerythrit-tetranitrate is recovered. Recovery of the other samples is below 1 %, indicating no mutual solubilities with supercritical carbon dioxide. Using modifiers, recoveries of nitro-triazole and cyclo-trimethylene-trinitramine can be greatly enhanced. 

For example, a mixture of 4 mol% 2-propanol with carbon dioxide extracts up to 35 percent of nitro-triazole and a mixture of 4 mol% acetonitrile extracts up to 95 percent of cyclo-trimethylene-trinitramine. 

Results indicate the good potential for pentaerythrit-tetranitrate in establishing the RESS process for the production of fine particles. The GAS process could be more suited for particle formation of nitroguanidine, cyclo-trimethylene-trinitramine and nitro-triazole. If additional small amounts of modifiers are acceptable, then the flexible handling of both RESS - and GAS-process can be proposed for cyclo-trimethylene-trinitramine and nitro-triazole. 

Amino-l-nitro-l,2,4-triazole (581), obtained by nitration of 5-amino-triazole with acetyl nitrate, rearranges, on heating, to the nitramino-triazole (582). ° The combined action of sodium hydroxide, potassium iodide, tri-ethylamine, and sodium dihydrogen phosphite on the chloro-nitro-triazole (583) results in a mixture of the rearranged triazole (584), 3-chloro-l,2,4-triazole, and the coupled product (585). The stable betaine (586) has been prepared by treatment of 4-phenyl-1,2,4-triazole with phenacyl bromide, followed by tri-ethylamine. The meso-ionic triazolium thiolate (537 X = S) reacts with chlorine to form the dichloride (587 X = SCU), which has been converted into the betaine (588) by the action of diethyl bromomalonate in the presence of triethylamine. ... 

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