Nitric microsensors

T. Malinski, Z.Taha, S. Grunfeld, A. Burewicz, P. Tomboulian, and F. Kiechle, Measurement of nitric oxide in biological materials using a porphyrinnic microsensor. Anal. Chim. Acta 279, 135—140 (1993). 

T. Malinski and Z. Taha, Nitric-oxide release from a single cell measured in situ by a porphyrinic-based microsensor. Nature 358, 676-678 (1992). 

T. Malinski, F. Bailey, Z.G. Zhang, and M. Chopp, Nitric-oxide measured by a porphyrinic microsensor in rat-brain after transient middle cerebral-artery occlusion. J. Cereb. Blood Flow Metab. 13, 355-358 (1993). 

D. Kato, M. Kunitake, M. Nishizawa, T. Matsue, and F. Mizutani, Amperometric nitric oxide microsensor using two-dimensional cross-linked Langmuir-Blodgett films of polysiloxane copolymer. Sens. Actuator B-Chem. 108, 384—388 (2005). 

J.H. Shin, S.W. Weinman, and M.H. Schoenfisch, Sol-gel derived amperometric nitric oxide microsensor. Anal. Chem. 77, 3494-3501 (2005). 

X.J. Zhang, L. Cardosa, M. Broderick, H. Fein, and I.R. Davies, Novel calibration method for nitric oxide microsensors by stoichiometrical generation of nitric oxide from SNAP. Electroanalysis 12, 425—428 (2000). 

A. J. Cunningham and J. B. Justice, Jr., Approaches to Voltammetric and Chromatographic Monitoring of Neurochemicals in Vivo, J. Chem. Ed. 1987, 64, A34. Another Nafion-coated electrode can detect 10 10 mol of the neurotransmitter nitric oxide within a single cell [T. Malinski and Z. Taha, Nitric Oxide Release from a Single Cell Measured in Situ by a Porphyrinic-Based Microsensor, Nature 1992, 358, 676]. 

Steven R. Tannenbaum, a member of the Institute of Medicine, has a Ph.D. in food science and technology from the Massachusetts Institute of Technology, where he is currently the codirector and Underwood-Prescott Professor, Division of Bioengineering and Environmental Health, and professor of chemistry, Department of Chemistry. Dr. Tannenbaum s research interests include the chemistry and pathophysiology of nitric oxide, the quantitative measurement of human exposure to carcinogens, and tissue-based microsensors for toxin detection and drug metabolism. He has been a member of the NRC Board on Environmental Studies and Toxicology and has served on several NRC committees. 

Malinski, T., Z. Taha, S. Grunfeld, S. Patton, M. Kapturczak, and P. Tomboulian (1993). Diffusion of nitric-oxide in the aorta wall monitored in-situ by porphyrinic microsensors. Sjoc/jem. Biophys. Res. Commun. 193(3), 1076-1082. 

Kanai, A.J., H.C. Strauss, G.A. Truskey, A. L. Crews, S. Grunfeld, and T. Malinski (1995). Shear-stress induces ATP-independent transient nitric-oxide release from vascular endothelial-cells, measured directly with a porphyrinic microsensor. Cir. Res. 77(2), 284-293. 

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