Niisslein-Volhard

Arora K, Niisslein-Volhard C 1992 Altered mitotic domains reveal fate map changes in Drosophila embryos mutant for zygotic dorsoventral patterning genes. Development 114 1003-1024... 

The elegant early work on homeotic genes has been summarized C. Niisslein-Volhard, Harvey Lectures 86 128-148 (1992) C. Nusslein-Volhard, JAMA 266 1848 9 (1991). 

Niisslein-Volhard found that this mRNA is translated soon after fertilization, and the Bicoid protein diffuses through... 

C. Niisslein-Volhard, Maternal effect mutations that alter the spatial coordinates for the embryo of Drosophila melanogaster. In Determinants of Spatial Organization. S. Subtelny and 1. Konigsberg, eds.. Academic Press, New York, 1979, pp. 185-211. 

Niisslein-Volhard, C., and E. Wieschaus. 1980. Mutations affecting segment number and polarity in Drosophila. Nature 287 795-801. 

Moussian, B., Schwarz, H., Bartoszewski, S., and C. Niisslein-Volhard. 2005. Involvement of chitin in exoskeleton morphogenesis in Drosophila melanogaster. Journal of Morphology 264 117-130. 

Wieschaus E. and Niisslein-Volhard D. 1986. Looking at embryos. In Drosophila A praaical approach (ed. D.B. Roberts). IRL Press, Washington, D.C. 

Lohs-Schardin M., Cremer C., and Niisslein-Volhard C. 1979a. A fate map for the larval epidermis of Drosophila melanogaster Localized cuticle defects following irradiation of the blastoderm with an ultraviolet laser microbeam. Dev. Biol. 73 239-255. 

Niisslein-Volhard C., Lohs-Schardin M., Sander K., and Cremer C. 1980. A dorso-ventral shift of embryonic primordia in a new maternal-effect mutant of Drosophila. Nature 283 474-476. 

Dark-field illumination is the most common technique for viewing larval cuticles, particularly for viewing large features such as the mouthparts, ventral denticle belts, and posterior spiracles. A handy substitute for true dark-field illumination is to use low-power objectives with the condenser set in the phase-contrast position for a higher-powered objective (Wieschaus and Niisslein-Volhard 1986). For example, use a lOx objective with the condenser in Ph3 position. Other larval features, e.g., the fine dorsal denticles of the first instar larva, are best observed using phase-contrast optics. 

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