Nickel-, Cobalt-, and Molybdenum-Catalyzed Indole Ring Syntheses

Nickel-, Cobalt-, and Molybdenum-Catalyzed Indole Ring Syntheses 

The Pauson-Khand reaction is a cobalt-assisted [2+2+2] cycloaddition involving an alkyne, an alkene, and carbon monoxide to give a cyclopentenone [5, 6]. By suitable substrate design, several investigators have applied the Pauson-Khand reaction to the synthesis of indoles. 

Indole Ring Synthesis From Natural Products to Drug Discovery, First Edition. Gordon W. Gribble. 2016 John Wiley Sons, Ltd. Published 2016 by John Wiley Sons, Ltd. 

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