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Neurotransmitter system glutamatergic systems

Cory-Slechta DA. 1995a. Relationships between lead-induced learning impairments and changes in dopaminergic, cholinergic, and glutamatergic neurotransmitter system functions. Annu Rev Pharmacol Toxicol 35 391-415. [Pg.504]

The first group includes the glutamatergic and GABAergic systems. These two classes of neurons are by far more prevalent and more widely distributed than any other neurotransmitter system in the human brain. The major functional implication of such widespread distribution is that the modulation of glutamatergic and GABAergic neurotransmission affects many neural systems. [Pg.23]

Recently, attempts have been made to reconcile the deficiencies in the dopamine hypothesis by focusing on other neurotransmitters that may interact with dopamine in discrete cortical and subcortical neural circuits. In particular, the involvement of the glutamatergic system has received considerable attention. This possibility has arisen from the finding that dissociation anaesthetics such as ketamine and phencyclidine (PCP) can cause a schizophreniform psychosis in normal individuals. Such effects bear a much closer resemblance to the positive and negative symptoms of... [Pg.259]

Heath PR, Shaw PJ. Update on the glutamatergic neurotransmitter system and the role of excitotoxicity in amyotrophic lateral sclerosis. Muscle Nerve 2002 26(4) 438 158. [Pg.289]

Popken GJ, Leggio MG, Bunney WE, Jones EG. 2002. Expression of mRNAs related to the GABAergic and glutamatergic neurotransmitter systems in the human thalamus Normal and schizophrenic. Thalamus Relat Syst 1 349-369. [Pg.487]

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