Neurochemical developmental patterns

Pharmacological Intervention in Autism to Restore Neurochemical Developmental Patterns... 

Bovolin P, Sanit M-R, Memo M, Costa E, Grayson DR. 1992a. Distinct developmental patterns of expression of the rat al, a5, ) 2S and > 2L GABA receptor mRNAs in vivo and in vitro. J Neurochem 59 62-72. 

This chapter is concerned with the neurochemical basis of developmental disability which is considered here in two forms the globally delayed or halted development seen in mental retardation, and the more circumscribed pattern of disordered development of autism. A range of deficits of important key aspects of consciousness are apparent in both conditions. Of particular relevance to consciousness are the cognitive and behavioural impairments in attention, concentration, memory, information processing and social behaviour which are commonly present. Consideration of aberrant neurotransmitter activities in these developmental deficits may provide insights into the role of neurotransmitters in consciousness. 

Suzuki, K., 1965, The pattern of mammalian brain gangliosides. III. Regional and developmental difference, J. Neurochem. 12 969. 

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