Neher

Eisenman, G., Sandblom, J., Neher, E. Metal-Ligand Interactions in Organic Chemistry and Biochemistry, Part 2, (eds. Pullman, B., Goldblum, N.), p. 1, D. Reidel, Dordrecht-Holland... 

We are grateful to.Professor H. Victor Neher of the Norman Bridge Laboratory of Physics for advice and instruction in silica-fiber technique. 

Mahrt RF, Haring Bolivar P, Pauck T, Wegmann G, Lemmer U, Siegner U, Hopmeier M, Hennig R, Scherf U, Mullen K, Kurz H, Bassler H, Gobel EO (1996) Phys Rev B 54 1759 Cimrovd V, Neher D, Scherf U (1996) Appl Phys Lett 69 608... 

Remmers M, Neher D, Griiner J, Friend RH, Gelnick GH, Warman JM, Quattrocchi C,... 

In a different context, a micropipette has been applied to monitor the current through a single-ion channel in a biological membrane. The patch-clamp technique invented by Sackmann and Neher [119] led to their Nobel Prize in medicine. The variations in channel current with voltage, concentration, type of ions, and type of channels have been explored. While the functions of specific channels, in particular their ionic selectivity, have been well known, only a handful of channels have the internal geometry and charge distribution determined. The development of a theory to interpret the mass of channel data and to predict channel action is still lacking. 

B Sackmann and E Neher, Single Channel Recording, Plenum, New York (1995). 

Pasti L, Zonta M, Pozzan T, Vicini S, Carmignoto G (2001) Cytosolic calcium oscillations in astrocytes may regulate exocytotic release of glutamate. J Neurosci 21 477 84 Fenner R, Neher E (1988) The role of calcium in stimulus-secretion coupling in excitable and non-excitable cells. J Exp Biol 139 329-345... 

Schipke CG, Kettenmann H (2004) Astrocyte responses to neuronal activity. Gha 47 226-232 Schneggenburger R, Neher E (2005) Presynaptic calcium and control of vesicle fusion. Curr Opin Neurobiol 15 266-274... 

The field of ion-channel research has met with intense interest during the past ten years. One reason for this development has been the advent of new methods such as the patch clamp technique invented by Sakmann and Neher [1] and new approaches to the cloning of the complete amino acid sequencing of ion channels as it was introduced by Numa and collaborators [2]. 

Neher and coworkers, for example, have used the whole-cell analysis of currents... 

P. L. Kirk and R. Craig (1948) have discussed the construction of fibre devices L. Walden (1937) has given a practical account of several uses of fibres as instrument suspensions D. R. Barber(1930) has described a device for mounting fibres with a degree of tension and H. V. Neher (1940) has given a very practical account of the manipulation of silica fibres. 

Neher, H. V., 1940, in Modern Physical Laboratory Practice by John Strong, Chap. 5 London Glasgow, Blackie. 

Urayama, K., Yamamoto, S., Tsujii, Y, Fukuda, T. and Neher, D. (2002) Elastic properties of well-defined, high-density poly(methyl methacrylate) brushes studied by electromechanical interferometry. Macromolecules, 35, 9459-9465. 

Kietzke, T, Neher, D., Kumke, M., Montenegro, R., Landfester, K. and Scherf, U. (2004) A nanoparticle approach to control the phase separation in polyfluorene photovoltaic devices. Macromolcculcs, 37, 4882 890. 

Conti, F., and E. Neher, Single channel recordings of K+ currents in squid axons, Nature, 285, 140 (1980). 

Sakmann, B., and E. Neher (Eds), Single-Channel Recordings, Plenum Press, New York, 1983. 

This is an important result. The simple open-channel block mechanism predicts that the total open time per burst is the same as the mean open time in the absence of blocker (Neher, 1983), even though openings are now chopped up by channel blockages. In fact, for channels that give bursts of openings in control recordings, the total open time per burst is constant in the presence or absence ... 

Neher, E., The charge carried by single-channel currents of rat cultured muscle cells in the presence of local anaesthetics. J. Physiol., 339, 663-678, 1983. 

E Neher, B Sakman, JH Steinbach. (1978). The extracellular patch clamp A method for resolving currents through individual open channels in biological membranes. Pfluegers Arch 375 219-228. 

OP Hamill, A Marty, E Neher, B Sakman, FJ Sigworth. (1981). Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pfluegers Arch 391 85-100. 

Neher, R. and Neher, E. (2004). Optimizing imaging parameters for the separation of multiple labels in a fluorescence image. J. Microsc. 213, 46-62. 

Neher, R. A. and Neher, E. (2004b). Applying spectral fingerprinting to the analysis of FRET images. Microsc. Res. Technol. 64, 185-95. 

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