Near microscopy

There has been extensive activity in the study of lipid monolayers as discussed above in Section IV-4E. Coexisting fluid phases have been observed via fluorescence microscopy of mixtures of phospholipid and cholesterol where a critical point occurs near 30 mol% cholesterol [257]. [Pg.144]

NSOM Near-Held scanning optical microscopy [103a] Light from a sharp tip scatters off sample Surface structure to 3 nm... [Pg.313]

Fleury L, Gruber A, Draebenstedt A, Wrachtrup J and von Borczyskowski C 1997 Low-temperature confocal microscopy on individual molecules near a surface J. Phys. Chem. B 101 7933-8... [Pg.1675]

B1.19.4 SCANNING NEAR-FIELD OPTICAL MICROSCOPY AND OTHER SPMS... [Pg.1715]

Of the methods described in this section, scaiming near-field optical microscopy (SNOM or NSOM) is tlie closest to being able to provide useful infonuation that is unobtainable by other means. Indeed, this teclmique has already been made available as a conunercial instmment. A detailed review of SNOM has been written by Pohl 11931. [Pg.1715]

B1.19.4.2 SCANNING NEAR-FIELD ACOUSTIC MICROSCOPY (SNAM)... [Pg.1717]

Pohl D W 1991 Soanning near-field optioal miorosoopy (SNOM) Advances/n Optical and Electron Microscopy yo 12, ed R Barer and V E Cosslett (London Aoademio)... [Pg.1729]

Durig U T, Pohl D W and Rohner F 1986 Near-field optical-scanning microscopy J. Appl. Phys. 59 3318 Pohl D W 1991 Scanning near-field optical microscopy (SNOM)/Icfr/. Opt. Electron. Microsc. 12 243... [Pg.1730]

Betzig E, Finn P L and Weiner J S 1992 Combined shear force and near-field scanning optical microscopy/4pp/. Phys. Lett. 60 2484... [Pg.1730]

Fischer U Ch, Durig U T and Pohl D W 1988 Near-field scanning microscopy in reflection Appl. Phys. Lett. 52 249 Cline J A, Barshatzky FI and Isaacson M 1991 Scanned-tip reflection-mode near-field scanning optical microscopy Ultramicroscopy 38 299... [Pg.1730]

Betzig E and Chichester R J 1993 Single molecules observed by near-field scanning optical microscopy Science 262 1422... [Pg.1730]

Takahashi S, Futamata M and Ko]ima I 1999 Spectroscopy with scanning near-field optical microscopy using photon tunnelling mode J. Microscopy 194 519... [Pg.1730]

Guenther P, Fischer U Ch and Dransfeld K 1989 Scanning near-field acoustic microscopy Appl. Phys. B 48 89 Williams C C and Wickramasinghe FI K 1986 Scanning thermal profiler App/. Phys. Lett. 49 1587... [Pg.1730]

One interesting new field in the area of optical spectroscopy is near-field scaiming optical microscopy, a teclmique that allows for the imaging of surfaces down to sub-micron resolution and for the detection and characterization of single molecules [, M]- Wlien applied to the study of surfaces, this approach is capable of identifying individual adsorbates, as in the case of oxazine molecules dispersed on a polymer film, illustrated in figure Bl.22,11 [82], Absorption and emission spectra of individual molecules can be obtamed with this teclmique as well, and time-dependent measurements can be used to follow the dynamics of surface processes. [Pg.1794]

Figure Bl.22.11. Near-field scanning optical microscopy fluorescence image of oxazine molecules dispersed on a PMMA film surface. Each protuberance in this three-dimensional plot corresponds to the detection of a single molecule, the different intensities of those features being due to different orientations of the molecules. Sub-diffraction resolution, in this case on the order of a fraction of a micron, can be achieved by the near-field scaiming arrangement. Spectroscopic characterization of each molecule is also possible. (Reprinted with pennission from [82]. Copyright 1996 American Chemical Society.)...

$Figure Bl.22.11. Near-field scanning optical microscopy fluorescence image of oxazine molecules dispersed on a PMMA film surface. Each protuberance in this three-dimensional plot corresponds to the detection of a single molecule, the different intensities of those features being due to different orientations of the molecules. Sub-diffraction resolution, in this case on the order of a fraction of a micron, can be achieved by the near-field scaiming arrangement. Spectroscopic characterization of each molecule is also possible. (Reprinted with pennission from [82]. Copyright 1996 American Chemical Society.)...$

A wide variety of measurements can now be made on single molecules, including electrical (e.g. scanning tunnelling microscopy), magnetic (e.g. spin resonance), force (e.g. atomic force microscopy), optical (e.g. near-field and far-field fluorescence microscopies) and hybrid teclmiques. This contribution addresses only Arose teclmiques tliat are at least partially optical. Single-particle electrical and force measurements are discussed in tire sections on scanning probe microscopies (B1.19) and surface forces apparatus (B1.20). [Pg.2483]

Hamann H F, Gallagher A and Nesbitt D J 1999 Enhanced sensitivity near-field scanning optical microscopy at high spatial resolution Appl. Phys. Lett. 75 1469-71... [Pg.2505]

Ambrose W P, Goodwin P M, Martin J C and Keller R A 1994 Alterations of single-molecule fluorescence lifetimes in near-field optical microscopy Science 265 364-7... [Pg.2505]

Bian R X, Dunn R C, Xie X S and Leung P T 1995 Single molecule emission characteristics in near-field microscopy Phys. Rev. Lett. 75 4772-5... [Pg.2505]

Higgins D A and Barbara P F 1995 Excitonic transitions in J-aggregates probed by near-field scanning optical microscopy J. Chem. Phys. 99 3-7... [Pg.2510]

Hollars C W and Dunn R C 2000 Probing single molecule orientations in model lipid membranes with near-field scanning optical microscopy J. Phys. Chem 112 7822-30... [Pg.2511]

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