Nardil

Narcotan - Halothane Narco26p Flunitrazepam Nardeizine Phenelzine sulfate Nardil - Phenelzine sulfate Narest Valethamate bromide Narigix Nalidixic acid Narsis - Medazepam Nasafarma - Oxymetazoline HCI Nazalide Flunisolide Nasal Yer Naphazoline Nasin Tetrahydrozoline HCI Nasivin - Oxymetazoline HCI Nasky Inositol niacinate Nasmil - Cromolyn sodium Nasophen - Phenylephrine HCI Natacillin - Hetacillln potassium Natacyn - Natamycin Natam - Flurazepam... 

With most psychedelics, their activity can probably be considerably enhanced by prior (or possibly concomitant) use of a monoamine oxidase inhibitor (e.g., isocarboxazid (Marplan), nialamide (Niamid), phenelzine (Nardil), and tranylcypromine (Parnate)). Some compounds (e.g., DMT) which have no oral activity, can probably become orally active. These compounds are often prescribed as antidepressants, but it is not a good idea to use them frequently or in large doses. For antidotes to the hallucinogens see Amer. J. Hosp. Pharm. 30,80(1973). 

In the United States, there are presently three approved MAOis phenelzine (Nardil), tranylcypromine (Parnate), and isocarboxizide (Marplan). These medications are all nonselective, irreversible inhibitors of the MAO enzymes. By nonselec-tive, it is meant that they block the actions of both the MAO-A and MAO-B enzyme subtypes. It is felt that blocking the MAO-B enzyme adds little to the effectiveness of these antidepressants but causes many of the problematic side effects. The MAOis are irreversible in that they deactivate the enzyme permanently. 

Monoamine Oxidase Inhibitors (MAOIs). Shortly after their introduction, MAOIs, snch as phenelzine (Nardil), were found to reduce the frequency of panic attacks. It became a standard treatment for what is now known as panic disorder nntil snpplanted by the benzodiazepines and SSRIs. Although all MAOIs are presumably effective for panic disorder, phenelzine is the best studied and has been shown to be effective at daily doses ranging from 45 to 90 mg. When used to treat panic disorder, phenelzine should be initiated at a dose of 15mg/day and gradually increased in 15 mg increments until reaching a therapeutic dose. 

Antidepressants. In the early 1980s, the recognition that depression is a frequent comorbid feature of BN coupled with the observation that appetite changes are a common feature of depression led researchers to evaluate antidepressant treatment for BN. Since that time, a series of controlled studies have demonstrated efficacy for a wide assortment of antidepressants including the TCAs imipramine (Tofranil) and desipramine (Norpramin), the MAOl phenelzine (Nardil), the SSRl fluoxetine (Prozac), and the atypical antidepressants trazodone (Desyrel) and bupropion (Wellbutrin). Overall, approximately two-thirds of antidepressant-treated patients with bulimia experience symptomatic improvement while nearly one-third achieves complete remission of binging and purging. In addition, the improvement in the symptoms of BN is not dependent on the presence of comorbid depression. 

There are curreutly three approved MAOI autidepressauts iu the Uuited States pheuelziue (Nardil), trauylcypromiue (Parnate), aud isocarboxizide (Marplau). These autidepressauts block both the MAO-A aud MAO-B subtypes. These MAOIs are also irreversible that is, they deactivate the euzyme permaueutly. 

Phenelzine is a MAO inhibitor which is used for treating patients with depressive characteristics such as atypical, nonendogenous, or neurotic conditions in which a combination of anxiety, depression, or phobia are observed. Phenelzine is not a drug of first choice, and it is used in depressions that do not respond to other medicinal drugs. Nardil is a synonym of phenelzine. 

Paroxetine (Paxil, Paxil CR) Phenelzine (Nardil) Selegiline transdermal (Emsam)... 

MAOI agents was synthesized and tested for antidepressant properties. Three MAOI agents are approved in the United States for use in major depression isocarboxazid (Marplan), phenelzine Nardil), and tranylcypromine (Parnate). 

C. Nortriptyline (Pamelor) is a TCA, and as a class these drugs require at least one steady-state blood level to safely and effectively use the medication. Paroxetine, venlafaxine, and bupropion have not had blood levels correlated to response, and their relatively low toxicity does not require therapeutic blood monitoring. Nardil is a MAOI, which can be... 

In the United States, the three MAOIS available for the treatment of psychiatric conditions are phenelzine (Nardil), tranylcypromine (Parnate), and isocarboxazid (Marplan). All three agents have indications for adult major depression (>16 years old) and, more specifically, atypical depression (anergia, hypersomnia, hy-perphagia, somatization, and anxiety symptoms). Although not indicated for anxiety, the MAOIs can also be particularly helpful in treatment of these disorders. Selegiline or L-deprenyl (Eldepryl) is also available in the United States and indicated for symptoms of Parkinson s disease and depression. 

Since MAOIs have dangerous risks and since other, less obviously dangerous antidepressants exist, MAOIs are not often prescribed. However, when SSRIs fail, MAOIs may be used and are effective in many cases. Two of the older MAOI drugs still used to treat anxiety disorders are phenelzine, which is sold under the brand name Nardil, and tranylcypromine, which is sold under the brand name Parnate. 

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