Nanoparticles with Toxic or Deleterious Health Effects

Nanoparticles with Toxic or Deleterious Health Effects 

In the national policy discussion of potential risks associated with nanotechnology, the discussion has been dominated by the possible health and environmental consequences associated with nanoengineered materials. A plethora of research has begun to explore the behavior of nanoengineered materials with physiological systems. The National Nanotechnology Initiative has also recommended several technical research needs and priorities for environmental, health, and safety of nanotechnology.  

The highest priority threats in this area include nanoparticles capable of destroying brain tissue or cells through inhalation or ingestion in food or water supplies. Studies of air pollution, particulate matter, and nanoparticle toxicology have lead to the development of a framework related to the potential consequences of inhalation exposure of nanoparticles, including lung inflammation and cardiovascular injury 

The potential consequences of inhalation exposure to nanoparticles are only beginning to be nnderstood. The toxicology of metal fumes, radionuclides, nuisance dusts, rat lung overload, the toxicology of sihca, asbestos, synthetic vitreous fibers, and pollution particles can aU be used to gain insight into the behavior of nanoparticles. Currently, there is no model to predict the toxicity or safety of nanoparticles, and little information is available with regard to human exposure and risks related to levels and duration of exposure. 

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