N-Octyl iodide

The oxazoline methodology can be applied in the total synthesis of natural products. For example, in the course of the total synthesis of European pine-saw fly pheromone 47, the key intermediate, chiral a-methyl carboxylic acid 46, was prepared via the reaction of a-lithioethyloxazoline with n-octyl iodide. The product 2-methyl decanoic acid 46 was obtained, after hydrolysis, in 72% ee (Scheme 2-26).51... 

Montanari and co-workers7 used polypode ligands (9) as phase-transfer catalysts. Thus, a saturated aqueous solution of K.I was stirred with n-octyl bromide in the presence of a multi-armed ligand the resulting production of n-octyl iodide was followed by gas chromatography. Catalyst activity was found to vary with the hydro-phobicity of the arms. When the chains are terminated by butyl groups, 72 hours... 

Yoon and Kim have prepared potassium triphenylborohydride (KPhjBH) and examined the reducing ability toward alkyl halides. n-Octyl iodide is reduced within 1 h at 0 °C, whereas n-octyl bromide takes 24 h for complete reduction. Secondary bromides are inert under these conditions. 

Octanol, 753 r-OctylazoBiethine, 213 n-Octyl iodide, 303 n-Octylmagnesium chloride, 415 n-Octylmercaptan, 1214... 

Aldehyde synthesis [before references], Franzen5 gives a procedure for drying trimethylamine oxide dihydrate (supplied by Beacon Chemicals) by mixing with dimethylformamide and distillation, eventually in vacuum, until the solvent is all removed. A solution of the residue in chloroform is treated with n-octyl iodide, added dropwise with stirring in 20-30 min. After refluxing for 20 min., the solution is cooled and treated with 2 N aqueous sulfuric acid at 50°. The chloroform layer is... 

Octene, 101 n-Octyl iodide, 434 A12-Oleanene, 238 Olefins, 280, 281 r/.v-Olefins, 356 Oleic acid, 310 Oligoribonucleotides, 271... 

PMMA cross-linked by ethylene dimethacrylate with immobilized side oligooxy-ethylene chains were used as interfacial transfer catalysts [80]. Also studied was the formation of benzyl acetate, benzyl bromide and alkali metal acetates in boiling chloroform and of n-octylphenyl ester from n-octyl iodide and K or Na phenoxide in toluene at 100 °C in the presence of a catalytic polymer amount. The product yield increased with an increase in the reaction time and the catalyst/acetate or catalyst/ phenoxide molar ratio. The conversion of benzyl bromide increased according to the following sequence of acetates Napolymeric catalyst could be regenerated and used many times. 

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