Myelin-associated glycoprotein multiple sclerosis

Wajgt A, Gorny M (1983) CSF antibodies to myelin basic protein and to myelin-associated glycoprotein in multiple sclerosis. Evidence of the intrathecal production of antibodies. Acta Neurol Scand 68 337-343. 

Thirty years ago, Quarles et al. described a heavily glycosylated protein from myelin preparatimis [4], which they called myelin-associated glycoprotein [5], abbreviated MAG. Over the following 10 years, Quarles and his coworkers characterized this protein before it drew further attention from other laboratories, induced by the seminal observatiOTi that MAG is developmentally regulated in myelinating cells [6] and is possibly involved in multiple sclerosis [7], two publications, which together have been cited over 500 times. 

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