Muscle relaxants hypersensitivity reactions

Bronchospasm occurs in more than half of the more severe hypersensitivity reactions, either on its own or as an accompaniment to other changes. It is more common, as one would expect, in asthmatic patients and in patients receiving muscle relaxants (where tracheal intubation may be a factor). It should, however, only be regarded as indicative of a reaction if other forms of airway obstruction and other causes of tracheal irritation have been excluded. 

DEPOLARIZING, NON-DEPOLARIZING VANCOMYCIN 1. t efficacy of these muscle relaxants 2. Possible risk of hypersensitivity reactions 1. Vancomycin has some neuromuscular blocking activity 2. Animal studies suggest additive effect on histamine release 1. Monitor neuromuscular blockade carefully 2. Be aware... 

Clemizole [ban, inn] is a benzimidazole, a histamine Hi-RECEPTOR ANTAGONIST with SEDATIVE actions. It has been used for hypersensitivity reactions, particularly as an antipruritic, clenbuterol [ban, inn] is a P-adrenoceptor agonist, which can be used as bronchodilator and uterine SMOOTH MUSCLE RELAXANT. It also has been used as an anabolic. Cleosin clindamycin. 

The therapeutic actions of H, antagonists include smooth muscle relaxation, decreased bronchial secretions, decreased allergic response, and sedation. They are therefore used to treat immediate hypersensitivity reactions, as cold remedies, to suppress motion sickness, and for sedation (the second-generation Hi antagonists [e.g., fexofenadine] do not pene-... 

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