Musca domestica production

One of the sex pheromone components of the housefly, Musca domestica, is Z9-21 H that is found on the cuticular surface of the fly. This compound is formed by the elongation of Z9-18 CoA using malonyl-CoA and NADPH to Z15-24 CoA which is decarboxylated to form Z9-21 Hc (Fig. 3) [78-80]. Other pheromone components include an epoxide and ketone that are produced from Z9-21 Hc by a cytochrome P450 [81,82] and methyl-branched alkanes that are produced by the substitution of methylmalonyl-CoA in place of malonyl-CoA at specific points during chain elongation [83,84]. A novel microsomal fatty acid synthase is involved in production of methyl-branched alkanes in most insects [85-87]. This fatty acid synthase is different from the ubiquitous soluble fatty acid synthase that produces saturated straight chain fatty acids in that it is found in the microsomes and prefers methylmalonyl-CoA. The amino acids valine and isoleucine can provide the carbon skeletons for methylmalonyl-CoA as well as propionate [83]. 

Adams T. S., Gerst J. W. and Masler E. P. (1997) Regulation of ovarian ecdysteroid production in the housefly, Musca domestica. Arch. Insect Biochem. Physiol. 35,135-148. 

Blomquist G. J., Tillman J. A., Reed J. R., Gu P., Vanderwel D., Choi S. and Reitz R. C. (1995) Regulation of enzymatic activity involved in sex pheromone production in the housefly, Musca domestica. Insect Biochem. Molec. Biol. 25, 751-757. 

Mpuru S., Blomquist G. J., Schal C., Roux M., Kuenzli M., Dusticier G., Clement J-L. and Bagneres A-G. (2001) Effect of age and sex on the production of internal and external hydrocarbons and pheromones in the housefly, Musca domestica. Insect Biochem. Mol. Biol. 31, 139-155. 

Blomquist, G.J. (2003). Ecdysteroid regulation of pheromone production in the housefly, Musca domestica. In Insect Pheromone Biochemistry and Molecular Biology, ed. G.J. Blomquist and R.G. Vogt. London Elsevier, pp. 231-252. 

The Swiss product DDT was introduced for housefly control in neutral countries in 1944, and already by 1946 resistance had developed in northern Sweden (of all unlikely places). When housefly resistance appeared near Rome, Italy in 1947, Professor Missiroli considered that it was a different subspecies which he named Musca domestica tiberina at the very same time that Wilson and Lindquist in the USDA Orlando laboratory were producing a resistant strain from a susceptible one by laboratory selection. 

E. coli 0157 H7 in flies collected from both dairy and beef cattle production environments (Alam and Zurek, 2004 Hancock et ah, 1998 Iwasa et ah, 1999 Shere et ah, 1998). Ely species shown to harbor this pathogen include members of the Muscidae and Calliphoridae families however, houseflies Musca domestica) are most typically implicated (Iwasa et ah, 1999 Keen et ah, 2006a Moriya et ah, 1999 Talley et ah, 2009). Alam and... 

The cis isomer of 9-tricosene is the sex pheromone of Musca domestica (housefly). It should be noted that cross-metathesis reactions involving unsymmetrical internal alkenes can lead to a complex product mixture, as self-metathesis and other cross-metathesis reactions also occur. 13-Heptacosene, the cis form of... 

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