Musca domestica Muscalure

A number of studies since 1980 have concentrated on the search for a sex pheromone analogous to Muscalure, the first contact pheromone discovered in mature Musca domestica females (Carlson et al., 1971). Other hydrocarbons have been described in various Diptera (Carlson et al., 1978 Blomquist and Jackson, 1979 El Messoussi et al., 1994 Blomquist, Chapter 8, in this volume). In all cases, a cuticular hydrocarbon with low or no volatility and high abundance was necessary, but not sufficient for a response. Its action could be checked only... 

Musca domestica, with its female-specific Muscalure - (Z)-9-tricosene - was first used as a model for biosynthetic studies (Blomquist and Jackson, 1979 Blomquist et al., 1987). Inspired by these model studies, Jallon (1984) proposed and discussed the first hypothetical pathway for the biosynthesis of major cuticular... 

Z)-9-Tricosene 382 (muscalure) together with a series of homologous alkenes was isolated as the sex-specific attractive basic component from faecal and cuticular lipids of the house fly Musca domestica 219). These alkenes, all possessing (Z)-configuration, were, in addition to other methods, synthesized by selective Wittig ole-... 

The sex attractant of fhe common housefly (Musca domestica) is a 23-carbon alkene with a cis double bond between atoms 9 and 10 called muscalure ... 

The sex attractant of the female housefly Musca domestica) is called muscaluie, and its structure follows. Outline a synthesis of muscalure, using the Wittig reaction. Will your synthesis lead to the required cis isomer ... 

Z)-9-Tricosene (muscalure), the sex pheromone of the housefly Musca domestica), has been prepared by this method in 69% yield and >99% purity. Extension of the methodology to trisub-... 

Propose a synthesis for (Z)-9-tricosene (muscalure), the sex pheromone for the common housefly (Musca domestica), starting with acetylene and haloaUcanes as sources of carbon atoms. 

Carbenes and Carbenoids A common housefly (Musca domestica). Commercially available traps with the attractant muscalure (synthesized via a route using an organometallic compound) combined with a poison are efficient at luring and killing houseflies (Section 15.2B). 

An acetylenic intermediate was used by Kovalev et al. (638) in their synthesis of muscalure (318), the sex pheromone of the house fly (Musca domestica). 

Kovalev, B. H., V. V. Stan, T. K. Antoch, V. P. Konyukhov, and S. F. Nedopekina Synthesis in field of attractants (sexual attractants) of insects. III. Easy method for preparation of higher dialkylacetylenes. Synthesis of muscalure, an indoor fly attractant for Musca domestica. Zh. Org. Khim. 13, 2049—2052 (1977). 

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