Murata studies

T. Bhaskar, K. Murai, T. Matsui, M.A. Brebu, M.A. Uddin, A. Muto, Y. Sakata, and K. Murata, Studies on thermal degradation of acrylonitrile-butadiene-styrene copolymer (ABS-br) containing brominated flame retardant, J. Anal. Appl. Pyrolysis, 70(2) 369-381, December 2003. 

Dopamine, a vasodilator, has been widely used for treatment of acute circulatory failure. However, since dopamine is rapidly metabolized when administered orally, its use has been limited to intravenous infusion. Murata et al., studied the bioavailability and the pharmacokinetics of orally administered dopamine (DA). The oral administration of DA to dogs resulted in an absolute bioavailability of approximately 3%. To minimize the extensive first-pass metabolism of DA, a dopamine prodrug, V-(/V-acetyl-l-mcLhionyl)-o,o-bis(cLhoxycarbonyl)dopamine (TA-870), was synthesized [28] (Fig. 6). Since DA is a substrate for both mono-... 

Araki, S, Murata, K, Aono, H. (1987). Central and peripheral nervous system dysfunction in workers exposed to lead, zinc and cooper. A follow-up study of visual and somatosensory evoked potentials. Int. Arch. Occup. Environ. Health, 59, 177-87. 

The homoaromatic interaction in other bridged annulenes has also been examined. The dications of several bridged annulenes were prepared and also studied theoretically and by NMR spectroscopy (Mullen et al., 1987 Wallraff et al., 1988). Once again homoaromatic interactions were deemed to be most important in determining the properties of these systems. Another cationic polycyclic potential homoaromatic system was investigated by Murata and Nakasuji (1980). They concluded, from NMR studies, that homoaromaticity was unimportant in the homophenalenyl cations [66], [67] and [68], (They reached the same conclusion for the corresponding anions.)... 

In situ generation of these cation-radicals has been used in their identification as biological metabolites. A valid alternative was to synthesize the cation-radical as a solid salt, isolate it, and investigate its reactions with various nucleophiles including DNA. Such studies were conducted to better understand the role of those intermediates in biological systems (Murata and Shine 1969, Ristagno and Shine 1971, Cremonesi et al. 1994, Stack et al. 1995). 

Sakata M, Maesato M, Miyazaki T, Nishimura K, Murata T, Yamochi H, Saito G (2008) High-pressure transport study of a charge-transfer salt based on cytosine and TCNQ using a diamond anvil cell. J Phys Conf Ser 132 012011/1-4... 

Sato K, Yamaura M, Hagiwara T, Murata K, Tokumoto M (1991) Study on the electrical conduction mechanism of polypyrrole films. Synth Met 40 35 8... 

Bimetallic Ni-based catalysts were also studied for SR of higher hydrocarbons in order to avoid the carbon formation and sulfur poisoning problems of conventional Ni catalysts.Murata et prepared a series of bimetallic catalysts by adding alkali and alkaline-earth metals to Ni catalyst supported on zirconia and alumina for SR of i-Cg and methylcyclohexane (MCFI). The performance of various bimetallic catalysts for SR of i-Cg and MCH are summarized in Figures 21a and 21b, respectively. It was reported that the stability of Ni/Zr02 is considerably improved by the addition of alkaline-earth metals (M), particularly strontium, to the catalyst with an M/Ni ratio of 0.5 by... 

The authors wish to thank Drs. Y. Tsubosaka, T. Murata, M. Hori, and H. Ozaki (University of Tokyo) for their contributions to these studies. 

S. Nakagawa, T. Ono, S. Murata, M. Nomura, and T. Sakai, in Catalysts in Petroleum Refining and Petrochemical Industries 1995, Studies in Surface Science and Catalysis, Vol. 100, M. Absi-Halabi, J. Beshara, H. Qabazard, and A. Stanislaus, eds., Elsevier, Amsterdam, 1996, p. 499. 

Shoko Yamazaki was born in Osaka, Japan. She studied chemistry at Osaka University and received her Ph.D. in 1986 under the supervision of Prof. Ichiro Murata. From 1985, she was an assistant lecturer at Nara University of Education. She joined the group of Professor Barry M. Trost as a visiting researcher at Stanford University (USA) in 1987-88. She became an assistant professor at Nara University of Education in 1989 and since 2003, a full professor of Nara University of Education. Her current main research interests are the development of new organic synthetic reactions. 

Mundy CJ, Colvin ME, Quong AA (2002) Irradiated guanine a Car-Parinello molecular dynamics study of dehydrogenation in the presence of an OH radical. J Phys Chem A 106 10063-10071 Murata-Kamiya N, Kamiya H, Muraoka M, Kaji H, Kasai H (1998) Comparison of oxidation products from DNA components byy-irradiation and Fenton-type reactions. J Radiat Res 38 121-131 Nabben FJ, van der Stroom HA, Loman H (1983) Inactivation of biologically active DNA by isopropanol and formate radicals. Int J Radiat Biol 43 495-504 Nakashima M, Hayon E (1979) Rates of reaction of inorganic phosphate radicals in solution. J Phys Chem 74 3290-3291... 

Murata et al. described studies of 1 1 mokmol solution mixtures of Ur6IN with an aminoxyl-functionalized complement, DAPN.181 These did not show solution-phase ESR signals attributable to radical pair formation. Given the... 

The initial charge distributions, which were recognized as very important, were analyzed in more detail in a number of works [32]. The analysis was extended to multichannel ionization [179], and the role of the excitation lifetime was specified [25]. A few articles devoted to them were published by Murata and Tachiya [26,27]. Earlier these authors studied experimentally the non-stationary kinetics of fluorescence quenching, which was fitted numerically... 

Yoshida, T., Hozyo, Y., and Murata, T., Studies on the development of tuberous roots in sweet potato (Ipomoea batatas, Lam. var. edulis, Mak.). The effect of deep placement of mineral nutrients on the tuber-yield of sweet potato, Proc. Crop Sci. Soc. Jpn., 39, 105-110, 1970. 

The purpose of the present experiments is to characterize kinetics parameters of p-nitrophenyl-/3-D-galactoside hydrolysis with / -galactosidase. Students will find out how to use absorption spectroscopy to study enzymatic properties of an enzyme (see also Murata et al. 2003). Before entering the lab, students should be able to explain the Beer-Lambert-Bouguer law and the basics of enzymology. 

Murata, T., Hattori, T., Amarume, S., Koichi, A. and Usui, T. (2003). Kinetic studies on endo-beta-galactosidase by a novel colorimetric assay and synthesis of N-acetyllactosamine-repeating oligosaccharide beta-glycosides using its transglycosylation activity. European Journal of Biochemistry, 270, 3709-3719. 

M. Adachi, Y. Murata, and S. Nakamura, Theoretical and experimental studies of indoaniline dyes. A novel relationship between absorption spectra and molecular structure, J. Am. Chem. Soc., 115, 4331-4338 (1993). 

Gas-phase study G. Schultz, I. Hargittai, Electron diffraction investigation of ethane-1,2-dithiol. Acta Chim. Hung. 1973, 75, 381-388 solid-state study M. Hayashi, Y. Shiro, T. Oshima, and H. Murata, The Vibrational Assignment, Rotational Isomerism and Force Constants of 1,2-Ethanedithiol. Bull. Chem. Soc. Japan 1965, 38, 1734-1740. 

For a review on selectivity in enzymatic reactions, see J. B. Jones, Aldrichimica Acta, 1993,26,105. For other studies on active site model for lipases, see K. Naemurz, R. Fukuda, M. Murata, M. Konishi, K. Hirose and Y. Tobe, Tetrahedron Asymm., 1995, 6, 2385. 

Naoki, H., Murata, M., and Yasumoto, T. 1993. Negative-ion fast-atom bombardment tandem mass spectrometry for the structural study of polyether compounds structural verification of yessotoxin. Rapid Commun. Mass Spectrom 7, 179-182. 

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