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Multiple ligand binding

Haiech, J. Klee, C.B. Demaille, J.G. Haiech, J. Effects of cations on affinity of calmodulin for calcium ordered binding of calcium ions allows the specific activation of calmodulin-stimulated enzymes. Theoretical approach to study of multiple ligand binding to a macromolecule. Biochemistry 1981, 20, 3890-3897. [Pg.370]

Harrelson JR Atkins WM, Nelson SD (2008) Multiple-ligand binding in CYP2A6 probing mechanisms of cytochrome P450 cooperativity by assessing substrate dynamics. Biochemistry 47 2978-2988... [Pg.167]

In this chapter, we discuss the use of spectroscopic approaches to study multiple-ligand binding phenomena and their rigorous thermodynamic anal3rses to obtain model-independent binding isotherms. In these approaches, one generally monitors a spectroscopic signal (absorbance, fluorescence, circular dichroism,... [Pg.143]

In the first step of the analysis of a multiple ligand binding S5rstem, the obtained values of 2vj, corresponding to given values of ASohs, are used to ... [Pg.149]

This is never a priori known for any multiple ligand binding system. However, the estimate of the degree of binding and the free ligand concentrations can be obtained by using the LBDF approach. [Pg.158]

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See also in sourсe #XX -- [ Pg.120 ]



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Binding multiple

Ligand multiple binding modes

Multiple ligand

Multiple ligand binding sites

Multiple ligand binding sites cooperativity

Multiple ligand binding sites independent

Multiple metal-ligand binding sites

Quantitative determination of equilibrium binding isotherms for multiple ligand-macromolecule interactions using spectroscopic methods

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