Multiple-antibiotic resistance

MRSA strains are a frequent problem in hospital infechon, such strains often showing multiple antibiotic resistance. Furthermore, increased resistance to some... 

Coldham, N. G. Woodward, M. J. Characterization of the Salmonella typhimurium proteome by semi-automated two dimensional HPLC-mass spectrometry Detection of proteins implicated in multiple antibiotic resistance. J. Proteome Res. 2004, 3,595-603. 

The preceding protocol can be successfully applied, essentially without modifications, to prepare active cell-free extracts from bacteria other than Escherichia coli (e.g., Bacillus stearothermophilus and clinical isolates of Pseudomonas aeruginosa bearing multiple antibiotic resistance). 

HTHMARR helix turn helix multiple antibiotic resistance protein AB 0(0) 0(0) ... 

Wang YC, Li WY, Wu DC, Wang JJ, Wu CH, Liao JJ, Lin CK. (2009) In vitro activity of 2-methoxy-l, 4-naphthoquinone and stigmasta-7,22-diene-3P-ol from Impatiens balsamina L. against multiple antibiotic-resistant Helicobacter pylori. Evid Based Complement. Alternat Med 9 1-8. 

Threlfall E.J., L.R. Ward, J.A. Skinner, and B. Rowe (1997). Increase in multiple antibiotic resistance in nontyphoidal Salmonella from humans in England and Wales A comparison of data for 1994 and 1996. Microbial Drug Resistance 3 263-266. 

DWM Crook, BG Spratt. Multiple antibiotic resistance in Streptococcus pneumoniae. Br Med Bull 54 595-610, 1998. 

Table 41 Distribution pattern of multiple antibiotic resistance in test bacteria...

Table 4.18 MULTIPLE ANTIBIOTIC RESISTANCE (MAR) IN GRAM-NEGATIVE...

Figure 2 Integrons, transposons, and R-plasmids often collect multiple antibiotic resistance genes. As a result, selection of one resistance mechanism coselects for resistance to additional resistance genes. The scheme shows a typical arrangement for an integron with associated integrase-encoding gene (int), a promoter to drive gene transcription (P), and antibiotic resistance elements (A- ).

Nikaido H. Multiple antibiotic resistance and efflux. Curr. Opin. Microbiol. 1998 1 516-523. 

Tomasz A. Multiple-antibiotic-resistant pathogenic bacteria. A report on the Rockefeller University Workshop. N Engl J Med 1994 330(17) 1247-51. 

A munber of antibiotics have been used to treat EPEC, but multiple-antibiotic resistance is common. The use of antibiotics remains controversial in EHEC infection." Their use may be harmful owing to lysis of bacteria leading to increased release of toxin and alteration of normal intracolonic bacterial flora thereby increasing the systemic absorption of the toxin. 

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