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Multidrug and toxic compound extrusion

Currently, five different molecular classes of mdr efflux pumps are known [5], While pumps of the the ATP-binding cassette (ABC) transporter superfamily are driven by ATP hydrolysis, the other four superfamilies called resistance-nodulation-division (RND), major facilitator superfamily (MFS), multidrug and toxic compound extrusion (MATE), and small multidrag resistance transporter (SMR) are driven by the proton-motive force across the cytoplasmic membrane. Usually a single pump protein is located within the cytoplasmic membrane. However, the RND-type pumps which are restricted to Gram-negative bacteria consist of two additional components, a periplasmic membrane fusion protein (MFP) which connects the efflux pump to an outer... [Pg.105]

Table 6.1 Abbreviations BAN, BANYULS bHLH, basic helix-loop-helix CHS, chalcone synthase CHI, chalcone isomerase DFR, dihydroflavonol reductase F3H, flavonol 3-hydroxylase F3 H, flavonoid 3 -hydroxylase FLS, flavonol synthase icx, increased chalcone synthase expression LDOX, leucoanthocyanidin dioxygenase LCR, leucoanthocyanidin reductase MATE, multidrug and toxic compound extrusion NR, not yet reported tt, transparent testa ttg, transparent testa glabrous the WD40 and WRKY transcription factors are named for conserved amino acid sequences within these proteins. PC = personal communication. Table 6.1 Abbreviations BAN, BANYULS bHLH, basic helix-loop-helix CHS, chalcone synthase CHI, chalcone isomerase DFR, dihydroflavonol reductase F3H, flavonol 3-hydroxylase F3 H, flavonoid 3 -hydroxylase FLS, flavonol synthase icx, increased chalcone synthase expression LDOX, leucoanthocyanidin dioxygenase LCR, leucoanthocyanidin reductase MATE, multidrug and toxic compound extrusion NR, not yet reported tt, transparent testa ttg, transparent testa glabrous the WD40 and WRKY transcription factors are named for conserved amino acid sequences within these proteins. PC = personal communication.
Multidrug and toxic compound extrusion (MATE) family... [Pg.364]

Hiasa, M., Matsumoto, T., Komatsu, T., Omote, H. and Moriyama, Y. (2007) Functional characterization of testis-specific rodent multidrug and toxic compound extrusion 2, a class III MATE-type polyspecific H+/organic cation exporter. American Journal of Physiology. Cell Physiology, 293, C1437-C1444. [Pg.319]

Chen, Y., Zhang, S., Sorani, M. and Giacomini, K.M. (2007) Transport of paraquat by human organic cation transporters and multidrug and toxic compound extrusion family. The Journal of Pharmacology and Experimental Therapeutics, 322, 695-700. [Pg.319]

Organic Cation Transporter Family Organic Cation Transporters (OCT, SLC22A) and Multidrug and Toxic Compound Extrusion Transporters (MATE)... [Pg.180]

The multidrug and toxic compound extrusion family (MATE)... [Pg.380]

Morita M, Shitan N, Sawada K et al (2009) Vacuolar transport of nicotine is mediated by a multidrug and toxic compound extrusion (MATE) transporter in Nicotiana tabacwn. Proc Natl Acad Sci USA 106 2447-2452... [Pg.199]

Shoji T, Winz R, Iwase T et al (2002) Expression patterns of two tobacco isoflavone reductase-like genes and their possible roles in secondary metabolism in tobacco. Plant Mol Biol 50 427 40 Shoji T, Inai K, Yazaki Y et al (2009) Multidrug and toxic compound extrusion-type transporters implicated in vacuolar sequestration of nicotine in tobacco roots. Plant Physiol 149 708-718 Shoji T, Kajikawa M, Hashimoto T (2010) Clustered transcription factors regulate nicotine biosynthesis. Plant Cell 22 3390-3409... [Pg.200]

See other pages where Multidrug and toxic compound extrusion is mentioned: [Pg.181]    [Pg.96]    [Pg.502]    [Pg.277]    [Pg.285]    [Pg.381]    [Pg.292]    [Pg.460]    [Pg.263]    [Pg.193]    [Pg.480]   


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