Multi-modular Synthases as Tools of the Synthetic Chemist

Multi-modular Synthases as Tools of the Synthetic Chemist 

Multi-Step Enzyme Catalysis Biotransformations and Chemoenzymatic Synthesis Edited by Eduardo Garcia-Junceda 

Copyright 2008 WILEY-VCH Verlag GmbH Co. KGaA, Weinheim ISBN 978-3-527-31921-3 

The natural diversity in molecular structure found within these groups points to the evolutionary logic behind modular systems for the synthesis of these types of secondary metabolites. The theoretical simplicity of this modular organization coupled with the near infinite permutations of possible molecular structures has fueled enormous academic and industrial efforts to understand and modify modular biosynthetic systems, and new pathways continue to be revealed in the pursuit of this objective [7-10, 17]. 

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