Pentobarbital Morphine

Figure 14. Correlation between left ventricular muscle volume estimated by Dynamic Spatial Reconstructor (DSR) (ordinate) and by postmortem measurements (abscissa). Volume of myocardium estimated by DSR is plotted for three separate measurements for each dog. Regression line was calculated using average of the three measurements by DSR and volume by postmortem study. The eight dogs used (2.5—32.5 kg) had morphine-pentobarbital anesthesia, end diastole, 0.06 s aperture, and superior vena cava injection of Iml/kg lohexol (Iwasaki etai, 1984a).

Crowley, T.J. Stynes, A.J. Hydinger, M. and Kaufman, I.C. Ethanol, methamphetamine. pentobarbital, morphine, and monkey soeial behavior. Arch Gen Psychiatry 31 829-838, 1974. 

Hill, H. F., Bell, E. C., and Wilder, A. (1967) Reduction of conditioned suppression Actions of morphine compared with those of amphetamine, pentobarbital, nalorphine, cocaine, LSD-25, and chlorpromazine. Arch. Int. Pharmacodyn., 165 212-225. 

Li M, Garner HR, Wessinger WD, McMiUan DE (1995) Effects of food deprivation and satiation on sensitivity to the discriminative-stimulus effects of pentobarbital in pigeons and morphine in rats. Behav Pharmacol 6 724-731... 

Male or female Beagle or Labrador-Harrier dogs weighing 15-25 kg are used for the test. The dog is anesthetized by intravenous injection of 35M0 mg/kg pentobarbital sodium followed by subcutaneous injection of 2 mg/kg morphine. Respiration is maintained through a tracheal tube with N2O/O2 (3 1) using a positive pressure respirator. 

Also analyzed acebutolol, acepromazine, acetaminophen, acetazolamide, acetophenazine, albuterol, amitriptyline, amobarbital, amoxapine, antipsrrine, atenolol, atropine, azata-dine, baclofen, benzocaine, bromocriptine, brompheniramine, brotizolam, bupivacaine, buspirone, butabarbital, butalbital, caffeine, carbamazepine, cetirizine, chlorqyclizine, chlordiazepoxide, chlormezanone, chloroquine, chlorpheniramine, chlorpromazine, chlorpropamide, chlorprothixene, chlorthalidone, chlorzoxazone, cimetidine, cisapride, clomipramine, clonazepam, clonidine, clozapine, cocaine, codeine, colchicine, qyclizine, (yclo-benzaprine, dantrolene, desipramine, diazepam, diclofenac, diflunisal, diltiazem, diphenhydramine, diphenidol, dipheno late, dipyridamole, disopyramide, dobutamine, doxapram, doxepin, droperidol, encainide, ethidium bromide, ethopropazine, fenoprofen, fentanyl, flavoxate, fluoxetine, fluphenazine, flurazepam, flurbiprofen, fluvoxamine, fii-rosemide, glutethimide, glyburide, guaifenesin, haloperidol, homatropine, hydralazine, hydrochlorothiazide, hydrocodone, hydromorphone, hydro g chloroquine, hydroxyzine, ibuprofen, imipramine, indomethacin, ketoconazole, ketoprofen, ketorolac, labetalol, le-vorphanol, lidocaine, loratadine, lorazepam, lovastatin, loxapine, mazindol, mefenamic acid, meperidine, mephenytoin, mepivacaine, mesoridazine, metaproterenol, methadone, methdilazine, methocarbamol, methotrexate, methotrimeprazine, methoxamine, methyl-dopa, methylphenidate, metoclopramide, metolazone, metoprolol, metronidazole, midazolam, moclobemide, morphine, nadolol, nalbuphine, naloxone, naphazoline, naproxen, nifedipine, nizatidine, norepinephrine, nortriptyline, oxazepam, oxycodone, oxymetazo-line, paroxetine, pemoline, pentazocine, pentobarbital, pentoxifylline, perphenazine, pheniramine, phenobarbital, phenol, phenolphthalein, phentolamine, phenylbutazone, phenyltoloxamine, phenytoin, pimozide, pindolol, piroxicam, pramoxine, prazepam, prazosin, probenecid, procainamide, procaine, prochlorperazine, procyclidine, promazine, promethazine, propafenone, propantheline, propiomazine, propofol, propranolol, protriptyline, quazepam, quinidine, quinine, racemethorphan, ranitidine, remoxipride, risperidone, salicylic acid, scopolamine, secobarbital, sertraline, sotalol, spironolactone, sulfinpyrazone, sulindac, temazepam, terbutaline, terfenadine, tetracaine, theophylline, thiethyl-perazine, thiopental, thioridazine, thiothixene, timolol, tocainide, tolbutamide, tolmetin, trazodone, triamterene, triazolam, trifluoperazine, triflupromazine, trimeprazine, trimethoprim, trimipramine, verapamil, warfarin, xylometazoline, yohimbine, zopiclone... 

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