Monounsaturated fatty studies

Levine, Y. K., Kolinski, A. and Skolnick, J. (1993). A lattice dynamics study of a Langmuir monolayer of monounsaturated fatty acids, J. Chem. Phys., 98, 7581-7587. 

Botazzi el al., 1985 Gibson el al., 1992 Lotti el al., 1980). In this study eight monounsaturated fatty acids were readily detected, with the major one being C18 1 with several minor ones, C14 l and C15 l, only detected in the enriched column fractions. The major Cl6 1 fatty acids identified in evening primrose were n-7 and n-9, which contrasted with borage oil that contained Cl6 1 (n-7) and 06 1 (n-5) (Wretensjo and Svensson, 1990). 

Therefore, the kinetics and the product yields of isomerization and thiol adduct formation for a variety of Z- and ii-monounsaturated fatty acid (MUFA) esters were studied. The reactions were initiated by continuous °Co y-irradiation of N20-saturated f rf-butanol solutions containing -mercaptoethanol and MUFA esters. The time-dependent isomerizations and thiol additions were analyzed on the basis of the radiation chemical yields of radicals and established rate data. The rate constants for the reversible RS addition, within experimental error, do not depend on the double bond position in the alkyl chains vide Table 6). 

What about the choices betw een carbohydrates, mono unsaturated fatty acids, and FUFAs Studies on monounsahirated fatty adds versus carbohydrates have shown that monounsaturated fatty acids provois a decrease in plasma TGs and an increase in HDL[Pg.366]

Early studies by Overath and Stumpf (P. Overath, 1964) established not only that the constituents of the avocado fatty acid synthesis system could be dissociated and reconstituted, but also that the heat stable fraction from E. coli known as acyl carrier protein (ACP) could replace the corresponding fraction from avocado. Plant ACPs share both extensive sequence homology and significant elements of three-dimensional structure with their bacterial counterparts. In plants, this small, acidic protein not only holds the growing acyl chain during fatty acid synthesis, but also is required for synthesis of monounsaturated fatty acids and plastidial glycerolipids. 

P450 enzymes activate substrates with C=C double bonds, for instance from monounsaturated fatty acids, to form epoxides as an initial step in their metabolism. Quite a few biochemical studies focused on the products observed from double-bond activation using, for example, propene, cyclohexene, and styrene as substrates (82-86). Subsequent computational studies provided... 

In a similar study using differential thermal analysis (DTA), the perturbation effects of fatty acids on the SC were studied (Tanojo et al., 1994). Thermal behavior of the SC revealed that saturated fatty adds easily mix with the skin lipids and monounsaturated fatty acids to form a separate domain containing mostly pure fatty acids within the SC lipids. Polyunsaturated fatty acids also formed separate domains, but the extent of thermal transition was more than that showed by saturated fatty acids and less than monounsaturated fatty acids. In a recent investigation, SEMs of the skin treated with 10% oleic acid in ethanolic solution showed generation of pores on the surface of epidermal comeocytes (Touitou et al., 2002). 

Berry, E.M., Eisenberg, S., Haratz, D., Friedlander, Y., Norman, Y, Kaufmann, N.A., and Stein, Y, Effects of diets rich in monounsaturated fatty acids on plasma lipoproteins—the Jerusalem Nutrition Study High MUFAs vs high PUFAs, Am. J. Clin. Nutr., 53, 899-907, 1991. 

---