Monochloromethyl ether

Monochlorethanoic Acid, Ethyl Ester Monochloroacetic Acid Monochlorobenzene Monochlorodifluoromethane Monochloromethyl Ether... 

Synonyms Osybis(chloremethane)i dlchlorodlmethyl etheri monochloromethyl ether HLM 1988... 

Methoxymethyl derivatives of polysilanes, which cannot be obtained from the corresponding chloromethyl compounds by nucleophilic substitution because of intramolecular rearrangement, are prepared successfully by the reaction of chloropolysilanes with monochloromethyl ether in the presence of magnesium in tetrahydrofuran. 

Anion exchange membranes can be made from the same crosslinked polystyrene membrane base by post-treatment with monochloromethyl ether and aluminum chloride to introduce chloromethyl groups into the benzene ring, followed by formation of quaternary amines with trimethyl amine ... 

Monochloromethyl ether has been prepared by saturating an aqueous solution of formaldehyde and methyl alcohol with hydrogen chloride 1 and by saturating a solution of trioxymethyl-ene in methyl alcohol with hydrogen chloride.2 The method which is described in the procedure is essentially that developed by Henry.3... 

MEIHYLtJRACIL, 17, 6J Monochloromethyl ether, 14, 92 Morland salt, 15, 75 Myristic acid, 18, S4 Myristyl alcohol, 10,64 Myristyl bromide, 15,26 16, 37... 

Acetonitrile s. under CHgOCH Cl Monochloromethyl ether acetonitrile Sym. pyrophosphoric acid diesters from phosphoric acid monoesters... 

N-Benzoyl-2-(3, 4 -dimethoxyphenyl)ethylamine treated 18 hrs. at room temp, with monochloromethyl ether in glacial acetic acid 2-benzoyl-6,7-dimethoxy-l,2,3,4-... 

A stirred suspension of thallous cyclopentadienide (prepared from cyclopenta-diene, thallous sulfate, and KOH under No, Y >91%) in dry ether treated gradually at -20° under N2 with monochloromethyl ether, after 5 hrs. the crude intermediate isolated, allowed to react 18 hrs. at 0° with 4 equivalents 2-dilor-acrylonitrile and cupric fluoroborate, the resulting crude bicyclic chloronitriie dissolved in dimethyl sulfoxide, and treated 1.5 hrs. at 30-35° with aq. KOH product. Overall Y 50-55%. E. J. Corey, U. Koelliker, and J. Neuffer, Am. Soc. 93, 1489 (1971) f. e. s. ibid. 93, 1491 electrophilic substitution of cyclopentadienide anions, review, s. M. I. Rybinskaya and L. M. Korneva, Russ. Chem. Rev. 40, 247 (1971) (Eng. transl.). 

Syntheses with methoxymethyllithium. A soln. of monochloromethyl ether in methylal added gradually with stirring to a suspension of powdered Li in methylal at —25 to —30° after the reaction has been started at 0°, then allowed to react with diethyl ketone diethyl(methoxymethyl)carbinol. Y 75%. F. e. s. U. Schollkopf and H. Kiippers, Tetrah. Let. 1964, 1503 Grignard syntheses with 1,1-alkoxyhalides in methylal s. E. Taeger, E. Kahlert, and H. Walter, J. pr. 28,13 (1965). 

Halogenethers (s. a. Alkoxy-halides, Dihalogenethers, Monochloromethyl ether) Halogenethyl. . . s. a. Chloro-ethyl. . . ... 

Ghloromethylation of poorly reactive rings with monochloromethyl ether... 

A mixture of the startg. K-phenolate and 18-crown-6 poly ether as solubilizing agent stirred 0.5 hr. at room temp, in dry acetonitrile, monochloromethyl ether... 

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