Molecular weight Molar mass

The sedimentation coefficient s°, or its normalized form 5 0 w function of the conformation and flexibility of a macromolecule (via its translational frictional property) and its mass. So if we are going to obtain conformation and flexibility information we need to know the molecular weight (molar mass)... 

Study object Small molecular weight (molar mass) organic compounds,... 

Historically, the target analytes in clinical mass spectrometric applications were small, volatile compounds that could be analyzed by GC-MS (see Chapter 4). With time, new chemical preparation techniques and derivatization schemes broadened the scope of these metabolites to include fatty acids, amino acids, intermediates of glucose oxidation, phospholipids, steroids, neurogenic amines, nucleic acids, etc. The molecular weights (molar masses) after derivatization were less than 1000 Da, a mass range easily within the limits of most conventional mass spectrometers. 

One problem with GC-MS, in addition to being labor intensive and having particularly long analysis times, was that higher molecular weight (molar mass) components or compounds with preformed cations (such as cholines or carnitine) are easily hydrolyzed and cannot be analyzed effectively using GC-MS. With the advent of new ionization techniques for LC effluents (see Section 4.1.2), such as electrospray ionization (see Section 2.1.15), more volatile and larger molecular mass compounds could be analyzed,... 

Molecular weight (molar mass) the mass in grams of one mole of a substance. 

With the definition of molecular weight (molar mass of lUPAC), we have... 

Thermodynamic exchange equilibrium constant or coefficient Boltzmann constant Molecular weight Molar mass... 

This chapter will present the very important kinetic properties of coUoids, and their motion under the influence of gravitational and centrifugal fields. Kinetic properties are important for many reasons, for example they provide methods for determining the molecular weight (molar mass) of colloidal particles, their size and shape - i.e. for the characterization of colloidal particles. Many of the methods we will see in this chapter have found widespread use in the study of biological and polymeric molecules. 

Both methods offer a way for determining the molecular weight (molar mass) of the dispersed particles, as shown in Equations 8.7 and 8.8, each having its own advantages and shortcomings. The derivation of these two equations is left as exercise (Problem 8.8). 

MOLECULAR WEIGHT (MOLAR MASS) CHANGES BY SEC AND MALDI... 

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