Molecular sensing/sensor

Haidekker MA, Akers W, Lichlyter D, Brady TP, Theodorakis EA (2005) Sensing of flow and shear stress using fluorescent molecular rotors. Sensor Lett 3 42 18... 

Pickup JC, Shaw GW, Claremont DJ. In vivo molecular sensing in diabetes mellitus an implantable glucose sensor with direct electron transfer. Diabetologia 1989, 32,213-217. 

A. Ueno, Fluorescent sensors and color-change indicators for molecules, Adv. Materials, 1993, 5, 132—134 A. Ueno, Fluorescent cyclodextrins for molecular sensing, Supratnol. Set, 3, 31-36 T. Aoyagi, A. Nakamura, H. Ikeda, T. Ikeda, H. Mihara, A. Ueno, Alizarin yellow-modified jS-cyclodextrin as a guest-responsive absorption change sensor. Anal. Chem., 1997, 69, 659-663. 

This chapter does not cover the use of metal ions as allosteric effectors (3), skeletal components (4) (see Crystal Engineering, Supramolecular Materials Chemistry), or sensing elements (5) (see Molecular Redox Sensors, Colorimetric Sensors and Luminescent Sensing, Supramolecular Devices). It also does not address the interaction of metal complexes with biological systems (see Synthetic Peptide-Based Receptors, Biological Small Molecules as Receptors, Molecular Recognition and Supramolecular Bioinorganic Chemistry, Supramolecular Aspects... 

Fig. 26 Sensing mechanism of the molecularly imprinted sensor array. Reprinted with permission...

During recent years the use of a modular approach in the design and synthesis of new fluorescent PET sensors has been at the fore of the research undertaken towards molecular sensing within our research group. 

Three different ways in which a zeolite membrane can contribute to a better sensor performance can be distinguished (i) the add-on selective adsorption or molecular sieving layer to the sensor improves selectivity and sensitivity, (ii) the zeolite layer acts as active sensing material and adds the selective adsorption and molecular sieving properties to this, and (iii) the zeohte membrane adds a catalytically active layer to the sensor, improving the selectivity by specific reactions. 

Particularly attractive for numerous bioanalytical applications are colloidal metal (e.g., gold) and semiconductor quantum dot nanoparticles. The conductivity and catalytic properties of such systems have been employed for developing electrochemical gas sensors, electrochemical sensors based on molecular- or polymer-functionalized nanoparticle sensing interfaces, and for the construction of different biosensors including enzyme-based electrodes, immunosensors, and DNA sensors. Advances in the application of molecular and biomolecular functionalized metal, semiconductor, and magnetic particles for electroanalytical and bio-electroanalytical applications have been reviewed by Katz et al. [142]. 

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