Anion molecular recognition

Lehn, J. M. Sonveaux, E. Willard, A. K. Molecular recognition. Anion cryptates of a macrobicyclic receptor molecule for linear triatomic species, J. Am. Chem. Soc. 1978,100, 4914-4916. 

Keywords Guanidinium Molecular recognition Anion receptor Sensing Supramolecular... 

Houk RJT, Tobey SL, Anslyn EV (2005) Abiotic Guanidinium Receptors for Anion Molecular Recognition and Sensing. 255 199-229 Hue I, see Brizard A (2005) 256 167-218... 

Seel, C., Galan, A., de Mendoza, J. Molecular Recognition of Organic Acids and Anions -Receptor Models for Carboxylates, Amino Acids, and Nucleotides. 175, 101-132 (1995). 

There are several cases that have addressed molecular recognition of chiral drugs by modified CDs127 as well as inclusion complexes of cationic, anionic and neutral organic compounds128 in order to understand the role of hydrophobic and electrostatic interactions between the functional groups on host and guest. 

M. W. Hosseini, A. J. Blacker, and J.-M. Lehn, Multiple molecular recognition and catalysis, nucleotide binding and ATP hydrolysis by a receptor molecule bearing an anion binding site, an intercalator group, and a catalytic site, J. Chem. Soc., Chem. Commun. 596(1988). 

Some of the materials highlighted in this review offer novel redox-active cavities, which are candidates for studies on chemistry within cavities, especially processes which involve molecular recognition by donor-acceptor ii-Jt interactions, or by electron transfer mechanisms, e.g. coordination of a lone pair to a metal center, or formation of radical cation/radical anion pairs by charge transfer. The attachment of redox-active dendrimers to electrode surfaces (by chemical bonding, physical deposition, or screen printing) to form modified electrodes should provide interesting novel electron relay systems. 

The molecular recognition of anionic guest species by positively chaiged or neutral receptors is a relatively new area of research of growing interest in view of the key roles that these anions play in biochemical and chemical processes. For this reason, as part of the electrochemical studies, we decided to examine the use of the redox-active ferrocenyl dendrimers 3 and 4 that contain multiple N-H linkages capable of participating in H-bonding, as well as characteristic internal cavities,... 

An obvious possibility in the design of supramolecular anion receptors is the incorporation of a metal center in with which the anion may form a coordinate bond. Some examples of this type (e.g. 36) have already been mentioned. This section discusses a number of other metal complexes capable of multipoint molecular recognition based upon binding anionic ligands to a metal center along with the incorporation of other stabilizing interactions. 

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