Molecular genetics plasmids

Muller, J., Dijl, J.V., Venema, G. and Bron, S. (1996) Cloning of heterologous genes specifying detrimental proteins on pUC-derived plasmids in Escherichia coli. Molecular Genetics and Genomics, 252, 207-211. 

When genetic information (nucleic acid) is transferred between different cells, species or genera it is often carried by a specialized DNA molecule called a vector. Viruses are natural vectors, as are some kinds of small independently replicating circular extra-chromosomal DNA molecules (plasmids). A few of the basic features of plasmids used in molecular biology are reviewed in Figure 2.6. 

A. General description Intron A (interferon alfa-2b recombinant) is a recombi-nantly derived water-soluble protein with a molecular weight of 19.3 kDa. It is obtained from the bacterial fermentation of a strain of Escherichia coli bearing a genetically engineered plasmid containing an interferon alfa-2b gene from human leukocytes. 

Harayama, S., Rekik, M., Wasserfallen, A. Bairoch, A. (1987). Evolutionary relationship between catabolic pathways for aromatics conservation of gene order and nucleotide sequences for catechol oxidation genes of pWWO and NAH7 plasmids. Molecular General Genetics, 210, 241-7. 

Tsuda, M. lino, I. (1987). Genetic analysis of a transposon carrying toluene degrading genes on TOL plasmid pWWO. Molecular and General Genetics, 210, 270-6. 

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