Molecular genetics human genome

Essential to the definition of Pharmacogenetics is the term genetic polymorphism. It is extrapolated that there are at least three million genetic polymorphisms in the human genome. Historically, a genetic polymorphism was defined as a genetic variation with a population frequency of 1% and above, but the larger inter-ethnic variation of population frequencies makes a strict definition based on such frequencies impractical. The most common molecular type of polymorphism is the... 

DNA analysis has become an invaluable tool having very many practical applications that aim to open new frontiers in science. The sequencing of the human genome will provide information that could be applied to the study of genetic disorders as well as complications affecting the behaviour of humans at molecular level. 

Although molecular genetics was rapidly increasing in complexity at the time, the Human Genome Project (HGP) that was born in the late 1980s... 

Understanding the molecular genetics of plant natural product pathways facilitates the engineering of these pathways for plant improvement and human benefit (see Chapter by Halkier et al). This chapter focuses attention on the need to start applying genomics technology to exotic species for development of biotech crops with novel natural products and with improved pest resistance and increased nutritional value. 

Due to the further development of methodologies and technical equipment, the focus of molecular genetics shifted from single genes to whole genomes. The systematic analysis of complete genomes - the Human Genome Project - as well... 

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