Molecular biological recognition

In the context of this book, the term bioactivity is mainly applied to polymers that incorporate elements capable of molecular biological recognition, such as peptide sequences serving as cell adhesion ligands and polyanionic sites that utilize electrostatic interactions for the biomimetic presentation of... 

Jones G, P Willett and R C Glen 1995b. Molecular Recognition of Receptor Sites Using a Geneti Algorithm with a Description of Desolvation. Journal of Molecular Biology 245 43-53. 

The present review intends to be illustrative rather than comprehensive, and focuses on the results of this study leading to the hypothesis 9 — the three-dimensional shape similarity between interacting groups in reacting molecules is responsible for more specific and precise molecular recognition than would otherwise be achieved — and on the explanation of biological recognition on this basis. 

Schulz, G. E. (1979). In Molecular Mechanism of Biological Recognition (M. Balaban, ed.), pp. 79-94. Elsevier/North-Holland Biomedical Press, New York. 

Cech TR, Herschlag D (1996) Group I ribozyme substrate recognition, catalytic strategies and comparative mechanistic analysis. In Eckstein F, Lilley DMJ (eds) Nucleic acids and molecular biology, vol 10, catalytic RNA. Springer, Berlin Heidelberg New York, P 1... 

Lee, J., Thompson, J.R., Botuyan, M.V. and Mer, G. (2008) Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor. Nature Structural S, Molecular Biology, 15, 109-111. 

Polymer-mediated self-assembly of nanoparticles provides a versatile and effective approach for the fabrication of new materials. This bottom-up strategy builds up nanocomposite materials from diverse nanosized building blocks by incorporation of molecular-level recognition sites. The flexibility and reversibUity of self-assembly processes imparted by specific molecular interactions facilitates the formation of defect-free superstmctures, and it can be further explored in fields ranging from electronics to molecular biology. 

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