Minimum inhibitory concentration values

Crude extracts prepared from different parts of Turkish T. baccata have also been evaluated for their antimycobacterial activity. A CHCI3 fraction of the heartwood and ethanol extract of the leaves exhibited a minimum inhibitory concentration value (MIC) against Mycobacterium tuberculosis H37Ra strain of 200 pg/mL [102]. 

Cinnamon oil and extracts possess various antimicrobial activities against several bacteria, fungi, etc. Aqueous extract from cinnamon (C. zeylanicum, Blume) inhibited the replication of the influenza virus (Mancini et al., 1999). Oral administration of t-cinnamaldehyde and Omethoxycinnamaldehyde inhibited candidiasis at a MIC (minimum inhibitory concentration) value of 0.03-0.05 mg/ml. 

Table 1 Minimum inhibitory concentration values of some biocide actives in ppm...

Although it is well known that most of the classical quaternary ammonium salts possess bactericidal activity [54] and have been used as disinfectants, little was known until very recently about the toxicity of new ILs [55]. It is evident that use of these liquids as green materials requires the consideration of their toxicity and their minimum inhibitory concentration values [56]. This situation is now rapidly changing and most of the data available indicate that 1,3-diaIkylimidazolium ILs display antimicrobial activity and that their biological activity is dependent on the N-alkyl chain lengths [57]. The relatively low values of acute toxicity of 3-hexyloxy-... 

Li et al. [23] have synthesized a series of arylhydrazone derivatives bearing a rhodanine moiety and evaluated as antibacterial activity against several different strains of gram-positive bacteria, including multidrug-resistant clinical isolates. Of all the compounds tested, IV and V were identified as the most effective, with minimum inhibitory concentration values of 2-4 pg/mL against methicillin-resistant and quinolone-resistant S. aureus. 

The synthesized compounds were tested for their in vitro activity against Mycobacterium tuberculosis H37Rv (MTB). Compound 268a showed the most promising result with an MIC (minimum inhibitory concentration) value of 1.98 pM against MTB. It was also up to 26 times more potent than ethambutol and pyrazinamide, the standard first line TB drugs. 

TABLE XX Minimum Inhibitory Concentration Values of 3-Arylmethylcephalosporins" ... 

TABLE XXIII Minimum Inhibitory Concentration Values" ... 

TABLE XXVIII Tube Dilution Minimum Inhibitory Concentration Values for 3-H- or Alkyl-Substituted Vinylcephalosporins" ... 

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