Mimosinic acid

Hydroxy-4-oxo-l,4-dihydro-l-pyridinyl)propanoic acid (mimosinic acid) H L... 

Fig. 2. Chemical stmctures of some major chemical constituents of Mimosa pudica. a) Mimosine, b) Mimosinic acid, c) Tyrosine, d) Mimosinamine, e) Potassium-5-O-yff-O-glucopyranosylgentisate,...

There still remains to be settled the point of attachment of the a-aminopropionic acid side-chain in leucenol. As the latter is unaffected by boiling hydrobromic or hydriodic acid, an ether linkage at C in 3-hydroxypyridone-4 is unlikely and as the side-chain is eliminated by either pyrolysis or the action of alkali C for the location, as suggested by Kostermanns see mimosine below) is improbable. The balance of evidence seems to be in favour of attachment to the N-atom and additional data supporting this view have been provided by Adams and Jones. ... 

Sabinic acid Juniperus sabina Mimosine Leucen glauca... 

Table 1 The tyrosinase inhibitory activities of compounds 3-7, as compared to the standard inhibitors (kojic acid and L-mimosine) [43]...

Hydrox5rpyranones and hydroxypyridinones give a range of colors, from orange through red to violet, with iron(III)-containing solutions (27). Early applications of the use of kojic acid for the colorimetric determination of iron (280), e.g., in iron ores (281), followed and complemented the recommendation, in 1930, that iron(III) be used for the determination of kojic acid - iron(III) was later used for the colorimetric determination of mimosine (282). Other early colorimetric analyses included methods developed for the determination of... 

The effects of leucaena and mimosine on nonruminants can be reduced to some extent by diet supplementation with ferrous sulfates. Mimosine forms a complex with iron, which is excreted in the feces. Zinc supplementation has reduced the toxicity in cattle and it is believed that copper and zinc ions bind more strongly to mimosine than most other amino acids. 

Non-protein amino acids Phytohemagglutinins (lectins) Selenocystathionin, L-mimosine... 

Some further toxic plant amino acids include the jV-methylpyridinone mimosine (DNA binding and damaging) and 2-methylenecyclopropylalanine (hypoglycin) and 2-methyl-enecyclopropylglycine that, respectively, yield 2-methylenecyclopropylacetylCoA and... 

Mimosine (= Leucaenol) Leucaena leucocephala (jumbie (pyridinone amino acid) bean), Mimosa pudica (Fabaceae)... 

Methylseleninic acid (=C H 3-Se(=0)-0 H) (selenium derivative) Methylselenol (— Methyl-SeH) (senenol) Mimosine ( Leucaenol) (pyridinone amino acid)... 

Ikegami, R, Mizuno, M. and Murakoshi, I. (1990) Enzymatic synthesis of the thyrotoxic amino acid, mimosine, by cysteine synthase. Phytochemistry, 29,3461-6. 

The procedure given here describes the preparation and use of N-(benzyloxycarbonyl)-L-serine p-lactone for the synthesis of a protected -substituted alanine, N - benzyloxycarbonyl)-P—(pyrazol-l-yl)-L-alanine. This compound occurs in watermelon seeds,9 and has been used as a histidine analog.Its synthesis illustrates how serine p-lactones can provide convenient access to other p-substituted alanines such as mimosine, willardiine, quisqualic acid, and stizolobic add which occur in higher plants.5a,io Many previous chemical syntheses of racemic pyrazolylalanine have been published the best of these routes appear to be from acetamidoacryiic acid (94-96% yield) and from 0-acetylserine (40-45%).The... 

---